General Structure Information 2e7h EPHB4 solution structure of the second fn3 domain from human ephrin type-b receptor 4 -1.0Å AUTH X.R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND FN3 DOMAIN FROMTITL 2 HUMAN EPHRIN TYPE-B RECEPTOR 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fbk RGS3 crystal structure of the c2 domain of the human regulator of g-protein signaling 3 isoform 6 (rgp3), northeast structural genomics consortium target hr5550a 2.0Å AUTH F.FOROUHAR,S.LEW,J.SEETHARAMAN,L.MAO,R.XIAO,AUTH 2 C.CICCOSANTI,E.L.FOOTE,R.SHASTRY,J.K.EVERETT,AUTH 3 R.NAIR,T.B.ACTON,B.ROST,G.T.MONTELIONE,J.F.HUNT,AUTH 4 L.TONGTITL CRYSTAL STRUCTURE OF THE C2 DOMAIN OF THE HUMANTITL 2 REGULATOR OF G-PROTEIN SIGNALING 3 ISOFORM 6TITL 3 […]
General Structure Information 3p0u NR2C2 crystal structure of the ligand binding domain of human testicular receptor 4 3.0Å AUTH X.E.ZHOU,K.M.SUINO-POWELL,Y.XU,C.W.CHAN,O.TANABE,S.W.KRUSE,AUTH 2 R.REYNOLDS,J.D.ENGEL,H.E.XUTITL THE ORPHAN NUCLEAR RECEPTOR TR4 IS A VITAMIN A-ACTIVATEDTITL 2 NUCLEAR RECEPTOR.REF J.BIOL.CHEM. V. 286 2877 2011REFN ISSN 0021-9258PMID 21068381DOI 10.1074/JBC.M110.168740 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 1xa6 CHN2 crystal structure of the human beta2-chimaerin 3.2Å AUTH B.CANAGARAJAH,F.C.LESKOW,J.Y.HO,H.MISCHAK,AUTH 2 L.F.SAIDI,M.G.KAZANIETZ,J.H.HURLEYTITL STRUCTURAL MECHANISM FOR LIPID ACTIVATION OF THETITL 2 RAC-SPECIFIC GAP, BETA2-CHIMAERIN.REF CELL(CAMBRIDGE,MASS.) V. 119 407 2004REFN ISSN 0092-8674PMID 15507211DOI 10.1016/J.CELL.2004.10.012 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1k5g RANBP1 crystal structure of ran-gdp-alfx-ranbp1-rangap complex 3.1Å AUTH M.J.SEEWALD,C.KORNER,A.WITTINGHOFER,I.R.VETTERTITL RANGAP MEDIATES GTP HYDROLYSIS WITHOUT AN ARGININETITL 2 FINGER.REF NATURE V. 415 662 2002REFN ISSN 0028-0836PMID 11832950DOI 10.1038/415662A Variant Set Distributions Mapped Variants
General Structure Information 1c07 EPS15 structure of the third eps15 homology domain of human eps15 -1.0Å AUTH J.L.ENMON,T.DE BEER,M.OVERDUINTITL SOLUTION STRUCTURE OF EPS15S THIRD EH DOMAINTITL 2 REVEALS COINCIDENT PHE-TRP AND ASN-PRO-PHE BINDINGTITL 3 SITES.REF BIOCHEMISTRY V. 39 4309 2000REFN ISSN 0006-2960PMID 10757979DOI 10.1021/BI9927383 Variant Set Distributions Mapped Variants
General Structure Information 3c59 GLP1R crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain 2.3Å AUTH S.RUNGE,H.THOGERSEN,K.MADSEN,J.LAU,R.RUDOLPHTITL CRYSTAL STRUCTURE OF THE LIGAND-BOUND GLUCAGON-LIKETITL 2 PEPTIDE-1 RECEPTOR EXTRACELLULAR DOMAINREF J.BIOL.CHEM. V. 283 11340 2008REFN ISSN 0021-9258PMID 18287102DOI 10.1074/JBC.M708740200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1wz9 SERPINB5 the 2.1 a structure of a tumour suppressing serpin 2.1Å AUTH R.H.LAW,J.A.IRVING,A.M.BUCKLE,K.RUZYLA,M.BUZZA,AUTH 2 T.A.BASHTANNYK-PUHALOVICH,T.C.BEDDOE,K.NGUYEN,AUTH 3 D.M.WORRALL,S.P.BOTTOMLEY,P.I.BIRD,J.ROSSJOHN,AUTH 4 J.C.WHISSTOCKTITL THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE HUMANTITL 2 TUMOR SUPPRESSOR MASPIN REVEALS A NOVELTITL 3 CONFORMATIONAL SWITCH IN THE G-HELIX.REF J.BIOL.CHEM. V. 280 22356 2005REFN ISSN 0021-9258PMID 15760906DOI 10.1074/JBC.M412043200 Variant Set […]
General Structure Information 3lmk GRM5 ligand binding domain of metabotropoc glutamate receptor mglur5 complexed with glutamate 2.44Å AUTH E.DOBROVETSKY,G.KHUTORESKAYA,A.SEITOVA,D.COSSAR,A.M.EDWARDS,AUTH 2 C.H.ARROWSMITH,C.BOUNTRA,J.WEIGELT,A.BOCHKAREVTITL METABOTROPIC GLUTAMATE RECEPTOR MGLUR5 COMPLEXED WITHTITL 2 GLUTAMATEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jdr AKT2 structure of pkb-beta (akt2) complexed with the inhibitor a- 443654 2.3Å AUTH T.G.DAVIES,M.L.VERDONK,B.GRAHAM,S.SAALAU-BETHELL,AUTH 2 C.C.F.HAMLETT,T.MCHARDY,I.COLLINS,M.D.GARRETT,AUTH 3 P.WORKMAN,S.J.WOODHEAD,H.JHOTI,D.BARFORDTITL A STRUCTURAL COMPARISON OF INHIBITOR BINDING TOTITL 2 PKB, PKA AND PKA-PKB CHIMERAREF J.MOL.BIOL. V. 367 882 2007REFN ISSN 0022-2836PMID 17275837DOI 10.1016/J.JMB.2007.01.004 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]