General Structure Information
| PDB ID | 3p0u |
| HGNC Gene Label(s) | NR2C2 |
| Structure Name | crystal structure of the ligand binding domain of human testicular receptor 4 |
| Resolution | 3.0Å |
| Reference | AUTH X.E.ZHOU,K.M.SUINO-POWELL,Y.XU,C.W.CHAN,O.TANABE,S.W.KRUSE,AUTH 2 R.REYNOLDS,J.D.ENGEL,H.E.XUTITL THE ORPHAN NUCLEAR RECEPTOR TR4 IS A VITAMIN A-ACTIVATEDTITL 2 NUCLEAR RECEPTOR.REF J.BIOL.CHEM. V. 286 2877 2011REFN ISSN 0021-9258PMID 21068381DOI 10.1074/JBC.M110.168740 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 222 |
| Number Of SNVs | 24 |
| Number Of Permutations | 23495 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.199 |
| p-value | 0.045 |
COSMIC
| Number Of Residues | 222 |
| Number Of SNVs | 3 |
| Number Of Permutations | 45 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.182 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 24 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.312 |
| p-value | 0.101 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
