Assessment of Structural Intolerance and Durability
General Structure Information 1em2 STARD3 star-related lipid transport domain of mln64 2.2Å AUTH Y.TSUJISHITA,J.H.HURLEYTITL STRUCTURE AND LIPID TRANSPORT MECHANISM OF A STAR-RELATEDTITL 2 DOMAIN.REF NAT.STRUCT.BIOL. V. 7 408 2000REFN ISSN 1072-8368PMID 10802740DOI 10.1038/75192 Variant Set Distributions Mapped Variants
General Structure Information 2he2 DLG2 crystal structure of the 3rd pdz domain of human discs large homologue 2, dlg2 1.5Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,AUTH 2 C.PHILLIPS,C.GILEADI,P.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINEDTITL 2 WITH THE HELP OF SELF-BINDING C-TERMINALTITL 3 EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped […]
General Structure Information 2qy7 CLINT1 crystal structure of human epsinr enth domain 2.0Å AUTH S.E.MILLER,B.M.COLLINS,A.J.MCCOY,M.S.ROBINSON,AUTH 2 D.J.OWENTITL A SNARE-ADAPTOR INTERACTION IS A NEW MODE OF CARGOTITL 2 RECOGNITION IN CLATHRIN-COATED VESICLES.REF NATURE V. 450 570 2007REFN ISSN 0028-0836PMID 18033301DOI 10.1038/NATURE06353 Variant Set Distributions Mapped Variants
General Structure Information 4hxi CUL3 crystal structure of klhl3/cul3 complex 3.51Å AUTH A.X.JI,G.G.PRIVETITL STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF KLHL3/CUL3TITL 2 COMPLEX AND IMPLICATIONS OF FHHT MUTATIONS IN CUL3 BINDINGREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1wgr GRB7 solution structure of the ra domain of human grb7 protein -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RA DOMAIN OF HUMAN GRB7TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2a8b PTPRR crystal structure of the catalytic domain of human tyrosine phosphatase receptor, type r 2.3Å AUTH J.ESWARAN,J.P.VON KRIES,B.MARSDEN,E.LONGMAN,J.E.DEBRECZENI,AUTH 2 E.UGOCHUKWU,A.TURNBULL,W.H.LEE,S.KNAPP,A.J.BARRTITL CRYSTAL STRUCTURES AND INHIBITOR IDENTIFICATION FOR PTPN5,TITL 2 PTPRR AND PTPN7: A FAMILY OF HUMAN MAPK-SPECIFIC PROTEINTITL 3 TYROSINE PHOSPHATASES.REF BIOCHEM.J. V. 395 483 2006REFN ISSN 0264-6021PMID 16441242DOI 10.1042/BJ20051931 Variant Set […]
General Structure Information 1y8p PDK3 crystal structure of the pdk3-l2 complex 2.63Å AUTH M.KATO,J.L.CHUANG,S.C.TSO,R.M.WYNN,D.T.CHUANGTITL CRYSTAL STRUCTURE OF PYRUVATE DEHYDROGENASE KINASE 3 BOUNDTITL 2 TO LIPOYL DOMAIN 2 OF HUMAN PYRUVATE DEHYDROGENASE COMPLEX.REF EMBO J. V. 24 1763 2005REFN ISSN 0261-4189PMID 15861126DOI 10.1038/SJ.EMBOJ.7600663 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2ebt KLF5 solution structure of three tandem repeats of zf-c2h2 domains from human kruppel-like factor 5 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THREE TANDEM REPEATS OFTITL 2 ZF-C2H2 DOMAINS FROM HUMAN KRUPPEL-LIKE FACTOR 5REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2miu FHL2 structure of fhl2 lim adaptor and its interaction with ski -1.0Å AUTH Y.YANG,Y.SUN,E.E.MEDRANO,X.TIAN,M.A.WEISSTITL STRUCTURE OF FHL2 LIM ADAPTOR AND ITS INTERACTION WITH SKIREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ecs EIF2B1 crystal structure of human eif2b alpha 2.65Å AUTH T.B.HIYAMA,T.ITO,H.IMATAKA,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF HUMAN TRANSLATIONTITL 2 INITIATION FACTOR 2BREF J.MOL.BIOL. V. 392 937 2009REFN ISSN 0022-2836PMID 19631657DOI 10.1016/J.JMB.2009.07.054 Variant Set Distributions Mapped Variants