Assessment of Structural Intolerance and Durability
General Structure Information 2k7p FLNA filamin a ig-like domains 16-17 -1.0Å AUTH O.K.HEIKKINEN,S.RUSKAMO,P.V.KONAREV,D.I.SVERGUN,AUTH 2 T.IIVANAINEN,S.M.HEIKKINEN,P.PERMI,H.KOSKELA,AUTH 3 I.KILPELAINEN,J.YLANNETITL ATOMIC STRUCTURES OF TWO NOVEL IMMUNOGLOBULIN-LIKETITL 2 DOMAIN PAIRS IN THE ACTIN CROSS-LINKING PROTEINTITL 3 FILAMINREF J.BIOL.CHEM. V. 284 25450 2009REFN ISSN 0021-9258PMID 19622754DOI 10.1074/JBC.M109.019661 Variant Set Distributions Mapped Variants
General Structure Information 3tyy LMNB1 crystal structure of human lamin-b1 coil 2 segment 2.4Å AUTH J.RUAN,C.XU,C.BIAN,R.LAM,J.P.WANG,J.KANIA,J.MIN,J.ZANGTITL CRYSTAL STRUCTURES OF THE COIL 2B FRAGMENT AND THE GLOBULARTITL 2 TAIL DOMAIN OF HUMAN LAMIN B1.REF FEBS LETT. V. 586 314 2012REFN ISSN 0014-5793PMID 22265972DOI 10.1016/J.FEBSLET.2012.01.007 Variant Set Distributions Mapped Variants
General Structure Information 3jxf PTPRZ1 ca-like domain of human ptprz 2.0Å AUTH S.BOUYAIN,D.J.WATKINSTITL THE PROTEIN TYROSINE PHOSPHATASES PTPRZ AND PTPRGTITL 2 BIND TO DISTINCT MEMBERS OF THE CONTACTIN FAMILY OFTITL 3 NEURAL RECOGNITION MOLECULES.REF PROC.NATL.ACAD.SCI.USA V. 107 2443 2010REFN ISSN 0027-8424PMID 20133774DOI 10.1073/PNAS.0911235107 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2pa2 RPL10 crystal structure of human ribosomal protein l10 core domain 2.5Å AUTH M.NISHIMURA,T.KAMINISHI,C.TAKEMOTO,M.KAWAZOE,AUTH 2 T.YOSHIDA,A.TANAKA,S.SUGANO,M.SHIROUZU,T.OHKUBO,AUTH 3 S.YOKOYAMA,Y.KOBAYASHITITL CRYSTAL STRUCTURE OF HUMAN RIBOSOMAL PROTEIN L10TITL 2 CORE DOMAIN REVEALS EUKARYOTE-SPECIFIC MOTIFS INTITL 3 ADDITION TO THE CONSERVED FOLDREF J.MOL.BIOL. V. 377 421 2008REFN ISSN 0022-2836PMID 18258260DOI 10.1016/J.JMB.2008.01.003 Variant Set Distributions Mapped Variants
General Structure Information 2jvn PARP1 domain c of human parp-1 -1.0Å AUTH Z.TAO,P.GAO,D.W.HOFFMAN,H.W.LIUTITL DOMAIN C OF HUMAN POLY(ADP-RIBOSE) POLYMERASE-1 IS IMPORTANTTITL 2 FOR ENZYME ACTIVITY AND CONTAINS A NOVEL ZINC-RIBBON MOTIF.REF BIOCHEMISTRY V. 47 5804 2008REFN ISSN 0006-2960PMID 18452307DOI 10.1021/BI800018A Variant Set Distributions Mapped Variants
General Structure Information 2m16 PSIP1 p75/ledgf pwwp domain -1.0Å AUTH J.O.EIDAHL,B.L.CROWE,J.A.NORTH,C.J.MCKEE,N.SHKRIABAI,L.FENG,AUTH 2 M.PLUMB,R.L.GRAHAM,R.J.GORELICK,S.HESS,M.G.POIRIER,AUTH 3 M.P.FOSTER,M.KVARATSKHELIATITL STRUCTURAL BASIS FOR HIGH-AFFINITY BINDING OF LEDGF PWWP TOTITL 2 MONONUCLEOSOMES.REF NUCLEIC ACIDS RES. V. 41 3924 2013REFN ISSN 0305-1048PMID 23396443DOI 10.1093/NAR/GKT074 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants