2JVN.A | PARP1

General Structure Information

PDB ID 2jvn
HGNC Gene Label(s) PARP1
Structure Name domain c of human parp-1
Resolution -1.0Å
Reference AUTH Z.TAO,P.GAO,D.W.HOFFMAN,H.W.LIUTITL DOMAIN C OF HUMAN POLY(ADP-RIBOSE) POLYMERASE-1 IS IMPORTANTTITL 2 FOR ENZYME ACTIVITY AND CONTAINS A NOVEL ZINC-RIBBON MOTIF.REF BIOCHEMISTRY V. 47 5804 2008REFN ISSN 0006-2960PMID 18452307DOI 10.1021/BI800018A

Variant Set Distributions

ExAC Variants

Number Of Residues 126
Number Of SNVs 34
Number Of Permutations 19125
Optimal Distance Threshold 7.0
K Statistic 0.036
p-value 0.664

Mapped Variants

[+] ExAC Missense Variants