General Structure Information
| PDB ID | 2ebt |
| HGNC Gene Label(s) | KLF5 |
| Structure Name | solution structure of three tandem repeats of zf-c2h2 domains from human kruppel-like factor 5 |
| Resolution | -1.0Å |
| Reference | AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THREE TANDEM REPEATS OFTITL 2 ZF-C2H2 DOMAINS FROM HUMAN KRUPPEL-LIKE FACTOR 5REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 93 |
| Number Of SNVs | 11 |
| Number Of Permutations | 2390 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.327 |
| p-value | 0.728 |
COSMIC
| Number Of Residues | 93 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2193 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.067 |
| p-value | 0.455 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 11 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.224 |
| p-value | 0.21 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis

