General Structure Information
| PDB ID | 4hxi |
| HGNC Gene Label(s) | CUL3 |
| Structure Name | crystal structure of klhl3/cul3 complex |
| Resolution | 3.51Å |
| Reference | AUTH A.X.JI,G.G.PRIVETITL STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF KLHL3/CUL3TITL 2 COMPLEX AND IMPLICATIONS OF FHHT MUTATIONS IN CUL3 BINDINGREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 346 |
| Number Of SNVs | 39 |
| Number Of Permutations | 16554 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.023 |
| p-value | 0.774 |
COSMIC
| Number Of Residues | 346 |
| Number Of SNVs | 3 |
| Number Of Permutations | 326 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.667 |
| p-value | 0.383 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 39 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 37.0 |
| K Statistic | 0.44 |
| p-value | 0.456 |