General Structure Information 1kq6 NCF1 p47phox px domain 1.18Å AUTH M.WAHL,H.DELBRUECK,H.OSCHKINAT,U.HEINEMANNTITL P47PHOX PX DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
Assessment of Structural Intolerance and Durability
General Structure Information 1kq6 NCF1 p47phox px domain 1.18Å AUTH M.WAHL,H.DELBRUECK,H.OSCHKINAT,U.HEINEMANNTITL P47PHOX PX DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1g1q SELP crystal structure of p-selectin lectin/egf domains 2.4Å AUTH W.S.SOMERS,J.TANG,G.D.SHAW,R.T.CAMPHAUSENTITL INSIGHTS INTO THE MOLECULAR BASIS OF LEUKOCYTETITL 2 TETHERING AND ROLLING REVEALED BY STRUCTURES OF P-TITL 3 AND E-SELECTIN BOUND TO SLE(X) AND PSGL-1.REF CELL(CAMBRIDGE,MASS.) V. 103 467 2000REFN ISSN 0092-8674PMID 11081633DOI 10.1016/S0092-8674(00)00138-0 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3sp8 HGF crystal structure of nk2 in complex with fractionated heparin dp10 1.86Å AUTH R.RECACHA,B.MULLOY,E.GHERARDITITL CRYSTAL STRUCTURE OF NK2 IN COMPLEX WITH FRACTIONATEDTITL 2 HEPARIN DP10REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1jey XRCC5 crystal structure of the ku heterodimer bound to dna 2.5Å AUTH J.R.WALKER,R.A.CORPINA,J.GOLDBERGTITL STRUCTURE OF THE KU HETERODIMER BOUND TO DNA ANDTITL 2 ITS IMPLICATIONS FOR DOUBLE-STRAND BREAK REPAIR.REF NATURE V. 412 607 2001REFN ISSN 0028-0836PMID 11493912DOI 10.1038/35088000 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2prt WT1 structure of the wilms tumor suppressor protein zinc finger domain bound to dna 3.15Å AUTH R.STOLL,B.M.LEE,E.W.DEBLER,J.H.LAITY,I.A.WILSON,AUTH 2 H.J.DYSON,P.E.WRIGHTTITL STRUCTURE OF THE WILMS TUMOR SUPPRESSOR PROTEINTITL 2 ZINC FINGER DOMAIN BOUND TO DNAREF J.MOL.BIOL. V. 372 1227 2007REFN ISSN 0022-2836PMID 17716689DOI 10.1016/J.JMB.2007.07.017 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3fju CPA1 ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase a1 1.6Å AUTH L.SANGLAS,F.X.AVILES,R.HUBER,F.X.GOMIS-RUTH,J.L.AROLASTITL MAMMALIAN METALLOPEPTIDASE INHIBITION AT THE DEFENSE BARRIERTITL 2 OF ASCARIS PARASITEREF PROC.NATL.ACAD.SCI.USA V. 106 1743 2009REFN ISSN 0027-8424PMID 19179285DOI 10.1073/PNAS.0812623106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4a5w C6 crystal structure of c5b6 3.5Å AUTH M.A.HADDERS,D.BUBECK,P.ROVERSI,S.HAKOBYAN,F.FORNERIS,AUTH 2 B.P.MORGAN,M.K.PANGBURN,O.LLORCA,S.M.LEA,P.GROSTITL ASSEMBLY AND REGULATION OF THE MEMBRANE ATTACK COMPLEXTITL 2 BASED ON STRUCTURES OF C5B6 AND SC5B9.REF CELL REP. V. 1 200 2012REFN ISSN 2211-1247PMID 22832194DOI 10.1016/J.CELREP.2012.02.003 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1mlw TPH1 crystal structure of human tryptophan hydroxylase with bound 7,8-dihydro-l-biopterin cofactor and fe(iii) 1.71Å AUTH L.WANG,H.ERLANDSEN,J.HAAVIK,P.M.KNAPPSKOG,AUTH 2 R.C.STEVENSTITL THREE-DIMENSIONAL STRUCTURE OF HUMAN TRYPTOPHANTITL 2 HYDROXYLASE AND ITS IMPLICATIONS FOR THETITL 3 BIOSYNTHESIS OF THE NEUROTRANSMITTERS SEROTONINTITL 4 AND MELATONINREF BIOCHEMISTRY V. 41 12569 2002REFN ISSN 0006-2960PMID 12379098DOI 10.1021/BI026561F Variant Set Distributions […]
General Structure Information 1czv F5 crystal structure of the c2 domain of human coagulation factor v: dimeric crystal form 2.4Å AUTH S.MACEDO-RIBEIRO,W.BODE,R.HUBER,M.A.QUINN-ALLEN,AUTH 2 S.W.KIM,T.L.ORTEL,G.P.BOURENKOV,H.D.BARTUNIK,AUTH 3 M.T.STUBBS,W.H.KANE,P.FUENTES-PRIORTITL CRYSTAL STRUCTURES OF THE MEMBRANE-BINDING C2TITL 2 DOMAIN OF HUMAN COAGULATION FACTOR V.REF NATURE V. 402 434 1999REFN ISSN 0028-0836PMID 10586886DOI 10.1038/46594 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1kwm CPB1 human procarboxypeptidase b: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (tafi) 1.6Å AUTH P.J.BARBOSA PEREIRA,S.SEGURA-MARTIN,B.OLIVA,AUTH 2 C.FERRER-ORTA,F.X.AVILES,M.COLL,F.X.GOMIS-RUTH,AUTH 3 J.VENDRELLTITL HUMAN PROCARBOXYPEPTIDASE B: THREE-DIMENSIONALTITL 2 STRUCTURE AND IMPLICATIONS FORTITL 3 THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFI).REF J.MOL.BIOL. V. 321 537 2002REFN ISSN 0022-2836PMID 12162965DOI 10.1016/S0022-2836(02)00648-4 Variant Set Distributions Ripley’s K Analysis Plots […]