General Structure Information
| PDB ID | 1jey |
| HGNC Gene Label(s) | XRCC5 |
| Structure Name | crystal structure of the ku heterodimer bound to dna |
| Resolution | 2.5Å |
| Reference | AUTH J.R.WALKER,R.A.CORPINA,J.GOLDBERGTITL STRUCTURE OF THE KU HETERODIMER BOUND TO DNA ANDTITL 2 ITS IMPLICATIONS FOR DOUBLE-STRAND BREAK REPAIR.REF NATURE V. 412 607 2001REFN ISSN 0028-0836PMID 11493912DOI 10.1038/35088000 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 530 |
| Number Of SNVs | 75 |
| Number Of Permutations | 55531 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.011 |
| p-value | 0.522 |
COSMIC
| Number Of Residues | 530 |
| Number Of SNVs | 5 |
| Number Of Permutations | 2685 |
| Optimal Distance Threshold | 41.0 |
| K Statistic | 0.3 |
| p-value | 0.477 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 75 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 43.0 |
| K Statistic | -0.305 |
| p-value | 0.218 |