General Structure Information
| PDB ID | 3fju |
| HGNC Gene Label(s) | CPA1 |
| Structure Name | ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase a1 |
| Resolution | 1.6Å |
| Reference | AUTH L.SANGLAS,F.X.AVILES,R.HUBER,F.X.GOMIS-RUTH,J.L.AROLASTITL MAMMALIAN METALLOPEPTIDASE INHIBITION AT THE DEFENSE BARRIERTITL 2 OF ASCARIS PARASITEREF PROC.NATL.ACAD.SCI.USA V. 106 1743 2009REFN ISSN 0027-8424PMID 19179285DOI 10.1073/PNAS.0812623106 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 307 |
| Number Of SNVs | 67 |
| Number Of Permutations | 8750 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.074 |
| p-value | 0.428 |
COSMIC
| Number Of Residues | 307 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1590 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.048 |
| p-value | 0.869 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 67 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.266 |
| p-value | 0.161 |