General Structure Information
| PDB ID | 1czv |
| HGNC Gene Label(s) | F5 |
| Structure Name | crystal structure of the c2 domain of human coagulation factor v: dimeric crystal form |
| Resolution | 2.4Å |
| Reference | AUTH S.MACEDO-RIBEIRO,W.BODE,R.HUBER,M.A.QUINN-ALLEN,AUTH 2 S.W.KIM,T.L.ORTEL,G.P.BOURENKOV,H.D.BARTUNIK,AUTH 3 M.T.STUBBS,W.H.KANE,P.FUENTES-PRIORTITL CRYSTAL STRUCTURES OF THE MEMBRANE-BINDING C2TITL 2 DOMAIN OF HUMAN COAGULATION FACTOR V.REF NATURE V. 402 434 1999REFN ISSN 0028-0836PMID 10586886DOI 10.1038/46594 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 159 |
| Number Of SNVs | 34 |
| Number Of Permutations | 12021 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.036 |
| p-value | 0.529 |
COSMIC
| Number Of Residues | 159 |
| Number Of SNVs | 7 |
| Number Of Permutations | 949 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.19 |
| p-value | 0.822 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 34 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.211 |
| p-value | 0.741 |