General Structure Information 1aye CPA2 human procarboxypeptidase a2 1.8Å AUTH I.GARCIA-SAEZ,D.REVERTER,J.VENDRELL,F.X.AVILES,AUTH 2 M.COLLTITL THE THREE-DIMENSIONAL STRUCTURE OF HUMANTITL 2 PROCARBOXYPEPTIDASE A2. DECIPHERING THE BASIS OFTITL 3 THE INHIBITION, ACTIVATION AND INTRINSIC ACTIVITYTITL 4 OF THE ZYMOGEN.REF EMBO J. V. 16 6906 1997REFN ISSN 0261-4189PMID 9384570DOI 10.1093/EMBOJ/16.23.6906 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2qxi KLK7 high resolution structure of human kallikrein 7 in complex with suc-ala-ala-pro-phe-chloromethylketone 1.0Å AUTH M.DEBELA,P.HESS,V.MAGDOLEN,N.M.SCHECHTER,T.STEINER,AUTH 2 R.HUBER,W.BODE,P.GOETTIGTITL CHYMOTRYPTIC SPECIFICITY DETERMINANTS IN THE 1.0 ATITL 2 STRUCTURE OF THE ZINC-INHIBITED HUMAN TISSUETITL 3 KALLIKREIN 7.REF PROC.NATL.ACAD.SCI.USA V. 104 16086 2007REFN ISSN 0027-8424PMID 17909180DOI 10.1073/PNAS.0707811104 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2zks GZMM structural insights into the proteolytic machinery of apoptosis- inducing granzyme m 2.7Å AUTH L.WU,L.WANG,G.HUA,K.LIU,X.YANG,Y.ZHAI,M.BARTLAM,F.SUN,Z.FANTITL STRUCTURAL BASIS FOR PROTEOLYTIC SPECIFICITY OF THE HUMANTITL 2 APOPTOSIS-INDUCING GRANZYME MREF J.IMMUNOL. V. 183 421 2009REFN ISSN 0022-1767PMID 19542453DOI 10.4049/JIMMUNOL.0803088 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3cki TIMP3 crystal structure of the tace-n-timp-3 complex 2.3Å AUTH M.WISNIEWSKA,P.GOETTIG,K.MASKOS,E.BELOUSKI,AUTH 2 D.WINTERS,R.HECHT,R.BLACK,W.BODETITL STRUCTURAL DETERMINANTS OF THE ADAM INHIBITION BYTITL 2 TIMP-3: CRYSTAL STRUCTURE OF THE TACE-N-TIMP-3TITL 3 COMPLEX.REF J.MOL.BIOL. V. 381 1307 2008REFN ISSN 0022-2836PMID 18638486DOI 10.1016/J.JMB.2008.06.088 Variant Set Distributions Mapped Variants
General Structure Information 3e4c CASP1 procaspase-1 zymogen domain crystal strucutre 2.05Å AUTH J.M.ELLIOTT,L.ROUGE,C.WIESMANN,J.M.SCHEERTITL CRYSTAL STRUCTURE OF PROCASPASE-1 ZYMOGEN DOMAIN REVEALSTITL 2 INSIGHT INTO INFLAMMATORY CASPASE AUTOACTIVATIONREF J.BIOL.CHEM. V. 284 6546 2009REFN ISSN 0021-9258PMID 19117953DOI 10.1074/JBC.M806121200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1nn6 CMA1 human pro-chymase 1.75Å AUTH K.K.REILING,J.KRUCINSKI,L.J.MIERCKE,W.W.RAYMOND,G.H.CAUGHEY,AUTH 2 R.M.STROUDTITL STRUCTURE OF HUMAN PRO-CHYMASE: A MODEL FOR THE ACTIVATINGTITL 2 TRANSITION OF GRANULE-ASSOCIATED PROTEASES.REF BIOCHEMISTRY V. 42 2616 2003REFN ISSN 0006-2960PMID 12614156DOI 10.1021/BI020594D Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3dpe MMP8 crystal structure of the complex between mmp-8 and a non- zinc chelating inhibitor 1.6Å AUTH G.POCHETTI,R.MONTANARI,C.GEGE,C.CHEVRIER,AUTH 2 A.G.TAVERAS,F.MAZZATITL EXTRA BINDING REGION INDUCED BY NON-ZINC CHELATINGTITL 2 INHIBITORS INTO THE S(1) SUBSITE OF MATRIXTITL 3 METALLOPROTEINASE 8 (MMP-8)REF J.MED.CHEM. V. 52 1040 2009REFN ISSN 0022-2623PMID 19173605DOI 10.1021/JM801166J Variant Set Distributions Ripley’s […]
General Structure Information 2c0y CTSS the crystal structure of a cys25ala mutant of human procathepsin s 2.1Å AUTH G.KAULMANN,G.J.PALM,K.SCHILLING,R.HILGENFELD,AUTH 2 B.WIEDERANDERSTITL THE CRYSTAL STRUCTURE OF A CYS25 -> ALA MUTANT OFTITL 2 HUMAN PROCATHEPSIN S ELUCIDATES ENZYME-PROSEQUENCETITL 3 INTERACTIONS.REF PROTEIN SCI. V. 15 2619 2006REFN ISSN 0961-8368PMID 17075137DOI 10.1110/PS.062401806 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1fuj PRTN3 pr3 (myeloblastin) 2.2Å AUTH M.FUJINAGA,M.M.CHERNAIA,R.HALENBECK,K.KOTHS,M.N.JAMESTITL THE CRYSTAL STRUCTURE OF PR3, A NEUTROPHIL SERINE PROTEINASETITL 2 ANTIGEN OF WEGENERS GRANULOMATOSIS ANTIBODIES.REF J.MOL.BIOL. V. 261 267 1996REFN ISSN 0022-2836PMID 8757293DOI 10.1006/JMBI.1996.0458 Variant Set Distributions Mapped Variants
General Structure Information 3fju CPA1 ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase a1 1.6Å AUTH L.SANGLAS,F.X.AVILES,R.HUBER,F.X.GOMIS-RUTH,J.L.AROLASTITL MAMMALIAN METALLOPEPTIDASE INHIBITION AT THE DEFENSE BARRIERTITL 2 OF ASCARIS PARASITEREF PROC.NATL.ACAD.SCI.USA V. 106 1743 2009REFN ISSN 0027-8424PMID 19179285DOI 10.1073/PNAS.0812623106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants