General Structure Information
| PDB ID | 1nn6 |
| HGNC Gene Label(s) | CMA1 |
| Structure Name | human pro-chymase |
| Resolution | 1.75Å |
| Reference | AUTH K.K.REILING,J.KRUCINSKI,L.J.MIERCKE,W.W.RAYMOND,G.H.CAUGHEY,AUTH 2 R.M.STROUDTITL STRUCTURE OF HUMAN PRO-CHYMASE: A MODEL FOR THE ACTIVATINGTITL 2 TRANSITION OF GRANULE-ASSOCIATED PROTEASES.REF BIOCHEMISTRY V. 42 2616 2003REFN ISSN 0006-2960PMID 12614156DOI 10.1021/BI020594D |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 222 |
| Number Of SNVs | 85 |
| Number Of Permutations | 7669 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.266 |
| p-value | 0.12 |
COSMIC
| Number Of Residues | 222 |
| Number Of SNVs | 4 |
| Number Of Permutations | 104 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.175 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 85 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.546 |
| p-value | 0.097 |