Assessment of Structural Intolerance and Durability
General Structure Information 2dl1 SPG20 solution structure of the mit domain from human spartin -1.0Å AUTH T.SUETAKE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE MIT DOMAIN FROM HUMANTITL 2 SPARTINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dnx STX12 solution structure of rsgi ruh-063, an n-terminal domain of syntaxin 12 from human cdna -1.0Å AUTH T.ABE,H.HIROTA,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-063, AN N-TERMINALTITL 2 DOMAIN OF SYNTAXIN 12 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l0y CHCHD4 complex hmia40-hcox17 -1.0Å AUTH L.BANCI,I.BERTINI,C.CEFARO,L.CENACCHI,S.CIOFI-BAFFONI,AUTH 2 I.C.FELLI,A.GALLO,L.GONNELLI,E.LUCHINAT,D.SIDERIS,AUTH 3 K.TOKATLIDISTITL MOLECULAR CHAPERONE FUNCTION OF MIA40 TRIGGERS CONSECUTIVETITL 2 INDUCED FOLDING STEPS OF THE SUBSTRATE IN MITOCHONDRIALTITL 3 PROTEIN IMPORT.REF PROC.NATL.ACAD.SCI.USA V. 107 20190 2010REFN ISSN 0027-8424PMID 21059946DOI 10.1073/PNAS.1010095107 Variant Set Distributions Mapped Variants
General Structure Information 3a4u MCFD2 crystal structure of mcfd2 in complex with carbohydrate recognition domain of ergic-53 1.84Å AUTH M.NISHIO,Y.KAMIYA,T.MIZUSHIMA,S.WAKATSUKI,H.SASAKAWA,AUTH 2 K.YAMAMOTO,S.UCHIYAMA,M.NODA,A.R.MCKAY,K.FUKUI,H.P.HAURI,AUTH 3 K.KATOTITL STRUCTURAL BASIS FOR THE COOPERATIVE INTERPLAY BETWEEN THETITL 2 TWO CAUSATIVE GENE PRODUCTS OF COMBINED FACTOR V AND FACTORTITL 3 VIII DEFICIENCY.REF PROC.NATL.ACAD.SCI.USA V. 107 4034 2010REFN ISSN 0027-8424PMID 20142513DOI 10.1073/PNAS.0908526107 […]
General Structure Information 2vgq MAVS crystal structure of human ips-1 card 2.1Å AUTH J.A.POTTER,R.E.RANDALL,G.L.TAYLORTITL CRYSTAL STRUCTURE OF HUMAN IPS-1 CASPASETITL 2 ACTIVATION RECRUITMENT DOMAINREF BMC STRUCT.BIOL. V. 8 11 2008REFN ISSN 1472-6807PMID 18307765DOI 10.1186/1472-6807-8-11 Variant Set Distributions Mapped Variants
General Structure Information 2www MMAA crystal structure of methylmalonic acidemia type a protein 2.64Å AUTH D.S.FROESE,G.KOCHAN,J.R.C.MUNIZ,X.WU,C.GILEADI,AUTH 2 E.UGOCHUKWU,E.KRYSZTOFINSKA,R.A.GRAVEL,U.OPPERMANN,AUTH 3 W.W.YUETITL STRUCTURES OF THE HUMAN GTPASE MMAA AND VITAMINTITL 2 B12-DEPENDENT METHYLMALONYL-COA MUTASE AND INSIGHTTITL 3 INTO THEIR COMPLEX FORMATION.REF J.BIOL.CHEM. V. 285 38204 2010REFN ISSN 0021-9258PMID 20876572DOI 10.1074/JBC.M110.177717 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4lir NUP35 crystal structure of a nucleoporin 35kda (nup35) from homo sapiens at 2.46 a resolution 2.46Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL CRYSTAL STRUCTURE OF A NUCLEOPORIN 35KDA (NUP35) FROM HOMOTITL 2 SAPIENS AT 2.46 A RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 3lre KIF18A crystal structure analysis of human kinesin-8 motor domain 2.2Å AUTH C.PETERS,K.BREJC,L.BELMONT,A.J.BODEY,Y.LEE,M.YU,J.GUO,AUTH 2 R.SAKOWICZ,J.HARTMAN,C.A.MOORESTITL INSIGHT INTO THE MOLECULAR MECHANISM OF THE MULTITASKINGTITL 2 KINESIN-8 MOTOR.REF EMBO J. V. 29 3437 2010REFN ISSN 0261-4189PMID 20818331DOI 10.1038/EMBOJ.2010.220 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3bbp GCC2 rab6-gtp:gcc185 rab binding domain complex 3.0Å AUTH A.S.BURGUETE,T.D.FENN,A.T.BRUNGER,S.R.PFEFFERTITL RAB AND ARL GTPASE FAMILY MEMBERS COOPERATE IN THETITL 2 LOCALIZATION OF THE GOLGIN GCC185.REF CELL(CAMBRIDGE,MASS.) V. 132 286 2008REFN ISSN 0092-8674PMID 18243103DOI 10.1016/J.CELL.2007.11.048 Variant Set Distributions Mapped Variants
General Structure Information 2diz TXNDC5 the solution structure of the third thioredoxin domain of human thioredoxin domain-containing protein 5 -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE THIRD THIOREDOXINTITL 2 DOMAIN OF HUMAN THIOREDOXIN DOMAIN-CONTAININGTITL 3 PROTEIN 5REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]