Assessment of Structural Intolerance and Durability
General Structure Information 1olm SEC14L2 supernatant protein factor in complex with rrr-alpha-tocopherylquinone: a link between oxidized vitamin e and cholesterol biosynthesis 1.95Å AUTH A.STOCKER,U.BAUMANNTITL SUPERNATANT PROTEIN FACTOR IN COMPLEX WITHTITL 2 RRR-ALPHA-TOCOPHERYLQUINONE: A LINK BETWEENTITL 3 OXIDIZED VITAMIN E AND CHOLESTEROL BIOSYNTHESISREF J.MOL.BIOL. V. 332 759 2003REFN ISSN 0022-2836PMID 12972248DOI 10.1016/S0022-2836(03)00924-0 Variant Set Distributions Ripley’s […]
General Structure Information 3f1i HGS human escrt-0 core complex 2.3Å AUTH X.REN,D.P.KLOER,Y.C.KIM,R.GHIRLANDO,L.F.SAIDI,G.HUMMER,AUTH 2 J.H.HURLEYTITL HYBRID STRUCTURAL MODEL OF THE COMPLETE HUMAN ESCRT-0TITL 2 COMPLEX.REF STRUCTURE V. 17 406 2009REFN ISSN 0969-2126PMID 19278655DOI 10.1016/J.STR.2009.01.012 Variant Set Distributions Mapped Variants
General Structure Information 3l81 AP4M1 crystal structure of adaptor protein complex 4 (ap-4) mu4 subunit c- terminal domain, in complex with a sorting peptide from the amyloid precursor protein (app) 1.6Å AUTH P.V.BURGOS,G.A.MARDONES,A.L.ROJAS,L.L.DASILVA,Y.PRABHU,AUTH 2 J.H.HURLEY,J.S.BONIFACINOTITL SORTING OF THE ALZHEIMERS DISEASE AMYLOID PRECURSORTITL 2 PROTEIN MEDIATED BY THE AP-4 COMPLEX.REF DEV.CELL V. 18 425 2010REFN ISSN […]
General Structure Information 3gb8 XPO1 crystal structure of crm1/snurportin-1 complex 2.9Å AUTH X.DONG,A.BISWAS,K.E.SUEL,L.K.JACKSON,R.MARTINEZ,H.GU,AUTH 2 Y.M.CHOOKTITL STRUCTURAL BASIS FOR LEUCINE-RICH NUCLEAR EXPORT SIGNALTITL 2 RECOGNITION BY CRM1.REF NATURE V. 458 1136 2009REFN ISSN 0028-0836PMID 19339969DOI 10.1038/NATURE07975 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2c0j TRAPPC3 crystal structure of the bet3-trs33 heterodimer 2.2Å AUTH M.-S.KIM,M.-J.YI,K.-H.LEE,J.WAGNER,C.MUNGER,Y.-G.KIM,AUTH 2 M.WHITEWAY,M.CYGLER,B.-H.OH,M.SACHERTITL BIOCHEMICAL AND CRYSTALLOGRAPHIC STUDIES REVEAL A SPECIFICTITL 2 INTERACTION BETWEEN TRAPP SUBUNITS TRS33P AND BET3PREF TRAFFIC V. 6 1183 2005REFN ISSN 1398-9219PMID 16262728DOI 10.1111/J.1600-0854.2005.00352.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants