Assessment of Structural Intolerance and Durability
General Structure Information 1j78 GC crystallographic analysis of the human vitamin d binding protein 2.31Å AUTH C.VERBOVEN,A.RABIJNS,M.DE MAEYER,H.VAN BAELEN,AUTH 2 R.BOUILLON,C.DE RANTERTITL A STRUCTURAL BASIS FOR THE UNIQUE BINDING FEATURESTITL 2 OF THE HUMAN VITAMIN D-BINDING PROTEIN.REF NAT.STRUCT.BIOL. V. 9 131 2002REFN ISSN 1072-8368PMID 11799400DOI 10.1038/NSB754 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3fy7 CLIC3 crystal structure of homo sapiens clic3 1.95Å AUTH D.R.LITTLER,L.J.BROWN,S.N.BREIT,A.PERRAKIS,P.M.G.CURMITITL STRUCTURE OF HUMAN CLIC3 AT 2 A RESOLUTIONREF PROTEINS V. 78 1594 2010REFN ISSN 0887-3585PMID 20146363DOI 10.1002/PROT.22675 Variant Set Distributions Mapped Variants
General Structure Information 2j5w CP ceruloplasmin revisited: structural and functional roles of various metal cation binding sites 2.8Å AUTH I.BENTO,C.PEIXOTO,V.N.ZAITSEV,P.F.LINDLEYTITL CERULOPLASMIN REVISITED: STRUCTURAL AND FUNCTIONALTITL 2 ROLES OF VARIOUS METAL CATION-BINDING SITES.REF ACTA CRYSTALLOGR.,SECT.D V. 63 240 2007REFN ISSN 0907-4449PMID 17242517DOI 10.1107/S090744490604947X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2v5p IGF2 complex structure of human igf2r domains 11-13 bound to igf-ii 4.1Å AUTH J.BROWN,C.DELAINE,O.J.ZACCHEO,C.SIEBOLD,AUTH 2 R.J.GILBERT,G.VAN BOXEL,A.DENLEY,J.C.WALLACE,AUTH 3 A.B.HASSAN,B.E.FORBES,E.Y.JONESTITL STRUCTURE AND FUNCTIONAL ANALYSIS OF THETITL 2 IGF-II/IGF2R INTERACTIONREF EMBO J. V. 27 265 2008REFN ISSN 0261-4189PMID 18046459DOI 10.1038/SJ.EMBOJ.7601938 Variant Set Distributions Mapped Variants
General Structure Information 2j3t TRAPPC6A the crystal structure of the bet3-trs33-bet5-trs23 complex. 2.4Å AUTH Y.KIM,S.RAUNSER,C.MUNGER,J.WAGNER,Y.SONG,M.CYGLER,T.WALZ,AUTH 2 B.OH,M.SACHERTITL THE ARCHITECTURE OF THE MULTISUBUNIT TRAPP I COMPLEXTITL 2 SUGGESTS A MODEL FOR VESICLE TETHERING.REF CELL(CAMBRIDGE,MASS.) V. 127 817 2006REFN ISSN 0092-8674PMID 17110339DOI 10.1016/J.CELL.2006.09.029 Variant Set Distributions Mapped Variants
General Structure Information 2zne PDCD6 crystal structure of zn2+-bound form of des3-23alg-2 complexed with alix abs peptide 2.2Å AUTH H.SUZUKI,M.KAWASAKI,T.INUZUKA,M.OKUMURA,T.KAKIUCHI,AUTH 2 H.SHIBATA,S.WAKATSUKI,M.MAKITITL STRUCTURAL BASIS FOR CA(2+)-DEPENDENT FORMATION OFTITL 2 ALG-2/ALIX PEPTIDE COMPLEX: CA(2+)/EF3-DRIVENTITL 3 ARGININE SWITCH MECHANISMREF STRUCTURE V. 16 1562 2008REFN ISSN 0969-2126PMID 18940611DOI 10.1016/J.STR.2008.07.012 Variant Set Distributions Mapped Variants
General Structure Information 3eh1 SEC24B crystal structure of the human copii-coat protein sec24b 1.8Å AUTH J.D.MANCIAS,J.GOLDBERGTITL STRUCTURAL BASIS OF CARGO MEMBRANE PROTEINTITL 2 DISCRIMINATION BY THE HUMAN COPII COAT MACHINERY.REF EMBO J. V. 27 2918 2008REFN ISSN 0261-4189PMID 18843296DOI 10.1038/EMBOJ.2008.208 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3kq4 CUBN structure of intrinsic factor-cobalamin bound to its receptor cubilin 3.3Å AUTH C.B.ANDERSEN,M.MADSEN,T.STORM,S.K.MOESTRUP,G.R.ANDERSENTITL STRUCTURAL BASIS FOR RECEPTOR RECOGNITION OFTITL 2 VITAMIN-B(12)-INTRINSIC FACTOR COMPLEXES.REF NATURE V. 464 445 2010REFN ISSN 0028-0836PMID 20237569DOI 10.1038/NATURE08874 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3eg9 SEC24D crystal structure of the mammalian copii-coat protein sec23/24 bound to the transport signal sequence of membrin 3.0Å AUTH J.D.MANCIAS,J.GOLDBERGTITL STRUCTURAL BASIS OF CARGO MEMBRANE PROTEIN DISCRIMINATION BYTITL 2 THE HUMAN COPII COAT MACHINERY.REF EMBO J. V. 27 2918 2008REFN ISSN 0261-4189PMID 18843296DOI 10.1038/EMBOJ.2008.208 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2l0t STAM2 solution structure of the complex of ubiquitin and the vhs domain of stam2 -1.0Å AUTH A.LANGE,D.HOELLER,H.WIENK,O.MARCILLAT,J.M.LANCELIN,O.WALKERTITL NMR REVEALS A DIFFERENT MODE OF BINDING OF THE STAM2 VHSTITL 2 DOMAIN TO UBIQUITIN AND DIUBIQUITIN.REF BIOCHEMISTRY V. 50 48 2011REFN ISSN 0006-2960PMID 21121635DOI 10.1021/BI101594A Variant Set Distributions Ripley’s K Analysis Plots Variant […]