General Structure Information
| PDB ID | 2diz |
| HGNC Gene Label(s) | TXNDC5 |
| Structure Name | the solution structure of the third thioredoxin domain of human thioredoxin domain-containing protein 5 |
| Resolution | -1.0Å |
| Reference | AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE THIRD THIOREDOXINTITL 2 DOMAIN OF HUMAN THIOREDOXIN DOMAIN-CONTAININGTITL 3 PROTEIN 5REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 110 |
| Number Of SNVs | 31 |
| Number Of Permutations | 8863 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.088 |
| p-value | 0.386 |
COSMIC
| Number Of Residues | 110 |
| Number Of SNVs | 4 |
| Number Of Permutations | 45 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.829 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 31 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.46 |
| p-value | 0.281 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
