Assessment of Structural Intolerance and Durability
General Structure Information 1eot CCL11 solution nmr structure of eotaxin, minimized average structure -1.0Å AUTH M.P.CRUMP,K.RAJARATHNAM,K.S.KIM,I.CLARK-LEWIS,AUTH 2 B.D.SYKESTITL SOLUTION STRUCTURE OF EOTAXIN, A CHEMOKINE THATTITL 2 SELECTIVELY RECRUITS EOSINOPHILS IN ALLERGICTITL 3 INFLAMMATION.REF J.BIOL.CHEM. V. 273 22471 1998REFN ISSN 0021-9258PMID 9712872DOI 10.1074/JBC.273.35.22471 Variant Set Distributions Mapped Variants
General Structure Information 4fsv HSPA2 crystal structure of a heat shock 70kda protein 2 (hspa2) from homo sapiens at 1.80 a resolution 1.8Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL CRYSTAL STRUCTURE OF A HEAT SHOCK 70KDA PROTEIN 2 (HSPA2)TITL 2 FROM HOMO SAPIENS AT 1.80 A RESOLUTIONREF TO […]
General Structure Information 4msv FASLG crystal structure of fasl and dcr3 complex 2.5Å AUTH W.LIU,U.A.RAMAGOPAL,C.ZHAN,J.B.BONANNO,R.C.BHOSLE,AUTH 2 S.G.NATHENSON,S.C.ALMOTITL CRYSTAL STRUCTURE OF FASL AND DCR3 COMPLEXREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1o1v FABP6 human ileal lipid-binding protein (ilbp) in complex with cholyltaurine -1.0Å AUTH M.KURZ,V.BRACHVOGEL,H.MATTER,S.STENGELIN,AUTH 2 H.THUERING,W.KRAMERTITL INSIGHTS INTO THE BILE ACID TRANSPORTATION SYSTEM:TITL 2 THE HUMAN ILEAL LIPID-BINDINGTITL 3 PROTEIN-CHOLYLTAURINE COMPLEX AND ITS COMPARISONTITL 4 WITH HOMOLOGOUS STRUCTURES.REF PROTEINS V. 50 312 2003REFN ISSN 0887-3585PMID 12486725DOI 10.1002/PROT.10289 Variant Set Distributions Ripley’s K […]
General Structure Information 1xkt FASN human fatty acid synthase: structure and substrate selectivity of the thioesterase domain 2.6Å AUTH B.CHAKRAVARTY,Z.GU,S.S.CHIRALA,S.J.WAKIL,AUTH 2 F.A.QUIOCHOTITL HUMAN FATTY ACID SYNTHASE: STRUCTURE AND SUBSTRATETITL 2 SELECTIVITY OF THE THIOESTERASE DOMAIN.REF PROC.NATL.ACAD.SCI.USA V. 101 15567 2004REFN ISSN 0027-8424PMID 15507492DOI 10.1073/PNAS.0406901101 Variant Set Distributions Mapped Variants
General Structure Information 1qk9 MECP2 the solution structure of the domain from mecp2 that binds to methylated dna -1.0Å AUTH R.I.D.WAKEFIELD,B.O.SMITH,X.NAN,A.FREE,A.SOTERIOU,AUTH 2 D.UHRIN,A.P.BIRD,P.N.BARLOWTITL THE SOLUTION STRUCTURE OF THE DOMAIN FROM MECP2TITL 2 THAT BINDS TO METHYLATED DNAREF J.MOL.BIOL. V. 291 1055 1999REFN ISSN 0022-2836 70PMID 10518942DOI 10.1006/JMBI.1999.3023 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1bqq MMP14 crystal structure of the mt1-mmp–timp-2 complex 2.75Å AUTH C.FERNANDEZ-CATALAN,W.BODE,R.HUBER,D.TURK,AUTH 2 J.J.CALVETE,A.LICHTE,H.TSCHESCHE,K.MASKOSTITL CRYSTAL STRUCTURE OF THE COMPLEX FORMED BY THETITL 2 MEMBRANE TYPE 1-MATRIX METALLOPROTEINASE WITH THETITL 3 TISSUE INHIBITOR OF METALLOPROTEINASES-2, THETITL 4 SOLUBLE PROGELATINASE A RECEPTOR.REF EMBO J. V. 17 5238 1998REFN ISSN 0261-4189PMID 9724659DOI 10.1093/EMBOJ/17.17.5238 Variant Set Distributions […]
General Structure Information 3fbk RGS3 crystal structure of the c2 domain of the human regulator of g-protein signaling 3 isoform 6 (rgp3), northeast structural genomics consortium target hr5550a 2.0Å AUTH F.FOROUHAR,S.LEW,J.SEETHARAMAN,L.MAO,R.XIAO,AUTH 2 C.CICCOSANTI,E.L.FOOTE,R.SHASTRY,J.K.EVERETT,AUTH 3 R.NAIR,T.B.ACTON,B.ROST,G.T.MONTELIONE,J.F.HUNT,AUTH 4 L.TONGTITL CRYSTAL STRUCTURE OF THE C2 DOMAIN OF THE HUMANTITL 2 REGULATOR OF G-PROTEIN SIGNALING 3 ISOFORM 6TITL 3 […]
General Structure Information 2g2b AIF1 nmr structure of the human allograft inflammatory factor 1 -1.0Å AUTH J.SONG,R.C.TYLER,C.L.NEWMAN,D.VINAROV,J.L.MARKLEYTITL NMR STRUCTURE OF THE HUMAN ALLOGRAFT INFLAMMATORYTITL 2 FACTOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ger PYCR1 crystal structure and oxidative mechanism of human pyrroline-5- carboxylate reductase 3.1Å AUTH Z.MENG,Z.LOU,Z.LIU,M.LI,X.ZHAO,M.BARTLAM,Z.RAOTITL CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE REDUCTASEREF J.MOL.BIOL. V. 359 1364 2006REFN ISSN 0022-2836PMID 16730026DOI 10.1016/J.JMB.2006.04.053 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants