General Structure Information
| PDB ID | 1xkt |
| HGNC Gene Label(s) | FASN |
| Structure Name | human fatty acid synthase: structure and substrate selectivity of the thioesterase domain |
| Resolution | 2.6Å |
| Reference | AUTH B.CHAKRAVARTY,Z.GU,S.S.CHIRALA,S.J.WAKIL,AUTH 2 F.A.QUIOCHOTITL HUMAN FATTY ACID SYNTHASE: STRUCTURE AND SUBSTRATETITL 2 SELECTIVITY OF THE THIOESTERASE DOMAIN.REF PROC.NATL.ACAD.SCI.USA V. 101 15567 2004REFN ISSN 0027-8424PMID 15507492DOI 10.1073/PNAS.0406901101 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 259 |
| Number Of SNVs | 67 |
| Number Of Permutations | 9925 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.22 |
| p-value | 0.03 |