General Structure Information
| PDB ID | 4fsv |
| HGNC Gene Label(s) | HSPA2 |
| Structure Name | crystal structure of a heat shock 70kda protein 2 (hspa2) from homo sapiens at 1.80 a resolution |
| Resolution | 1.8Å |
| Reference | AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL CRYSTAL STRUCTURE OF A HEAT SHOCK 70KDA PROTEIN 2 (HSPA2)TITL 2 FROM HOMO SAPIENS AT 1.80 A RESOLUTIONREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 375 |
| Number Of SNVs | 64 |
| Number Of Permutations | 33041 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.276 |
| p-value | 0.789 |
COSMIC
| Number Of Residues | 375 |
| Number Of SNVs | 9 |
| Number Of Permutations | 4042 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.056 |
| p-value | 0.147 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 64 |
| Number Of COSMIC SNVs | 9 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.409 |
| p-value | 0.094 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
