Assessment of Structural Intolerance and Durability
General Structure Information 4kng RNF43 crystal structure of human lgr5-rspo1-rnf43 2.5Å AUTH P.H.CHEN,X.CHEN,Z.LIN,D.FANG,X.HETITL THE STRUCTURAL BASIS OF R-SPONDIN RECOGNITION BY LGR5 ANDTITL 2 RNF43.REF GENES DEV. V. 27 1345 2013REFN ISSN 0890-9369PMID 23756651DOI 10.1101/GAD.219915.113 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4k81 GRB14 crystal structure of the grb14 ra and ph domains in complex with gtp- loaded h-ras 2.4Å AUTH R.QAMRA,S.R.HUBBARDTITL STRUCTURAL BASIS FOR THE INTERACTION OF THE ADAPTOR PROTEINTITL 2 GRB14 WITH ACTIVATED RAS.REF PLOS ONE V. 8 72473 2013REFN ESSN 1932-6203PMID 23967305DOI 10.1371/JOURNAL.PONE.0072473 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4lp5 AGER crystal structure of the full-length human rage extracellular domain (vc1c2 fragment) 3.8Å AUTH L.YATIME,G.R.ANDERSENTITL STRUCTURAL INSIGHTS INTO THE OLIGOMERIZATION MODE OF THETITL 2 HUMAN RECEPTOR FOR ADVANCED GLYCATION END-PRODUCTS.REF FEBS J. V. 280 6556 2013REFN ISSN 1742-464XPMID 24119142DOI 10.1111/FEBS.12556 Variant Set Distributions Mapped Variants
General Structure Information 2rn9 COX17 solution structure of human apocox17 -1.0Å AUTH L.BANCI,I.BERTINI,S.CIOFI-BAFFONI,A.JANICKA,AUTH 2 M.MARTINELLI,H.KOZLOWSKI,P.PALUMAATITL A STRUCTURAL-DYNAMICAL CHARACTERIZATION OF HUMANTITL 2 COX17REF J.BIOL.CHEM. V. 283 7912 2008REFN ISSN 0021-9258PMID 18093982DOI 10.1074/JBC.M708016200 Variant Set Distributions Mapped Variants
General Structure Information 2yqg DSG2 solution structure of the first cadherin domain from human desmoglein-2 -1.0Å AUTH R.SANO,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST CADHERIN DOMAINTITL 2 FROM HUMAN DESMOGLEIN-2REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2yw5 BRD3 solution structure of the bromodomain from human bromodomain containing protein 3 -1.0Å AUTH M.FURUE,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE BROMODOMAIN FROM HUMANTITL 2 BROMODOMAIN CONTAINING PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1upt GOLGA4 structure of a complex of the golgin-245 grip domain with arl1 1.7Å AUTH B.PANIC,O.PERISIC,D.B.VEPRINTSEV,R.L.WILLIAMS,AUTH 2 S.MUNROTITL STRUCTURAL BASIS FOR ARL1-DEPENDENT TARGETING OFTITL 2 HOMODIMERIC GRIP DOMAINS TO THE GOLGI APPARATUSREF MOL.CELL V. 12 863 2003REFN ISSN 1097-2765PMID 14580338DOI 10.1016/S1097-2765(03)00356-3 Variant Set Distributions Mapped Variants
General Structure Information 2kle PKD2 isic refined solution structure of the calcium binding domain of the c-terminal cytosolic domain of polycystin-2 -1.0Å AUTH F.H.SCHUMANN,H.HOFFMEISTER,M.SCHMIDT,R.BADER,AUTH 2 E.BESL,R.WITZGALL,H.R.KALBITZERTITL NMR-ASSIGNMENTS OF A CYTOSOLIC DOMAIN OF THETITL 2 C-TERMINUS OF POLYCYSTIN-2REF BIOMOL.NMR ASSIGN. V. 3 141 2009REFN ISSN 1874-2718PMID 19636966DOI 10.1007/S12104-009-9160-X Variant Set Distributions Mapped Variants
General Structure Information 2bkf NBR1 structure of the pb1 domain of nbr1 1.56Å AUTH S.MUELLER,I.KURSULA,P.ZOU,M.WILMANNSTITL CRYSTAL STRUCTURE OF THE PB1 DOMAIN OF NBR1REF FEBS LETT. V. 580 341 2006REFN ISSN 0014-5793PMID 16376336DOI 10.1016/J.FEBSLET.2005.12.021 Variant Set Distributions Mapped Variants
General Structure Information 2edn MYBPC2 solution structure of the first ig-like domain from human myosin-binding protein c, fast-type -1.0Å AUTH K.NAGASHIMA,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST IG-LIKE DOMAINTITL 2 FROM HUMAN MYOSIN-BINDING PROTEIN C, FAST-TYPEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants