General Structure Information
| PDB ID | 4k81 |
| HGNC Gene Label(s) | GRB14 |
| Structure Name | crystal structure of the grb14 ra and ph domains in complex with gtp- loaded h-ras |
| Resolution | 2.4Å |
| Reference | AUTH R.QAMRA,S.R.HUBBARDTITL STRUCTURAL BASIS FOR THE INTERACTION OF THE ADAPTOR PROTEINTITL 2 GRB14 WITH ACTIVATED RAS.REF PLOS ONE V. 8 72473 2013REFN ESSN 1932-6203PMID 23967305DOI 10.1371/JOURNAL.PONE.0072473 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 244 |
| Number Of SNVs | 77 |
| Number Of Permutations | 36193 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.095 |
| p-value | 0.149 |
COSMIC
| Number Of Residues | 244 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1883 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.1 |
| p-value | 0.274 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 77 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.093 |
| p-value | 0.102 |