Assessment of Structural Intolerance and Durability
General Structure Information 2lxs CREBBP allosteric communication in the kix domain proceeds through dynamic re-packing of the hydrophobic core -1.0Å AUTH S.BRUSCHWEILER,R.KONRAT,M.TOLLINGERTITL ALLOSTERIC COMMUNICATION IN THE KIX DOMAIN PROCEEDS THROUGHTITL 2 DYNAMIC REPACKING OF THE HYDROPHOBIC CORE.REF ACS CHEM.BIOL. 2013REFN ESSN 1554-8937PMID 23651431DOI 10.1021/CB4002188 Variant Set Distributions Mapped Variants
General Structure Information 1olz SEMA4D the ligand-binding face of the semaphorins revealed by the high resolution crystal structure of sema4d 2.0Å AUTH C.A.LOVE,K.HARLOS,N.MAVADDAT,S.J.DAVIS,D.I.STUART,AUTH 2 E.Y.JONES,R.M.ESNOUFTITL THE LIGAND-BINDING FACE OF THE SEMAPHORINSTITL 2 REVEALED BY THE HIGH-RESOLUTION CRYSTAL STRUCTURETITL 3 OF SEMA4DREF NAT.STRUCT.BIOL. V. 10 843 2003REFN ISSN 1072-8368PMID 12958590DOI 10.1038/NSB977 Variant Set Distributions Ripley’s K […]
General Structure Information 2cto MAEL solution structure of the hmg box like domain from human hypothetical protein flj14904 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 Y.O.KAMATARI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HMG BOX LIKE DOMAIN FROMTITL 2 HUMAN HYPOTHETICAL PROTEIN FLJ14904REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1×40 ARAP2 solution structure of the sam domain of human arap2 -1.0Å AUTH A.SASAGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SAM DOMAIN OF HUMAN ARAP2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3gvp AHCYL2 human sahh-like domain of human adenosylhomocysteinase 3 2.25Å AUTH M.I.SIPONEN,M.WISNIEWSKA,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 C.BOUNTRA,R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,AUTH 4 T.KARLBERG,T.KOTENYOVA,L.LEHTIO,M.MOCHE,P.NORDLUND,AUTH 5 T.NYMAN,C.PERSSON,J.SAGEMARK,P.SCHUTZ,A.G.THORSELL,AUTH 6 L.TRESAUGUES,S.VAN DEN BERG,J.WEIGELT,M.WELIN,AUTH 7 H.SCHUELERTITL HUMAN S-ADENOSYL HOMOCYSTEINE HYDROLASE-LIKE 2TITL 2 PROTEIN CRYSTAL STRUCTUREREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 3dqv CUL5 structural insights into nedd8 activation of cullin-ring ligases: conformational control of conjugation 3.0Å AUTH D.M.DUDA,L.A.BORG,D.C.SCOTT,H.W.HUNT,M.HAMMEL,AUTH 2 B.A.SCHULMANTITL STRUCTURAL INSIGHTS INTO NEDD8 ACTIVATION OFTITL 2 CULLIN-RING LIGASES: CONFORMATIONAL CONTROL OFTITL 3 CONJUGATION.REF CELL(CAMBRIDGE,MASS.) V. 134 995 2008REFN ISSN 0092-8674PMID 18805092DOI 10.1016/J.CELL.2008.07.022 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1ttn UBTD2 solution structure of the ubiquitin-like domain of human dc- ubp from dendritic cells -1.0Å AUTH Y.G.GAO,A.X.SONG,Y.H.SHI,Y.G.CHANG,S.X.LIU,Y.Z.YU,AUTH 2 X.T.CAO,D.H.LIN,H.Y.HUTITL SOLUTION STRUCTURE OF THE UBIQUITIN-LIKE DOMAIN OFTITL 2 HUMAN DC-UBP FROM DENDRITIC CELLSREF PROTEIN SCI. V. 14 2044 2005REFN ISSN 0961-8368PMID 15987890DOI 10.1110/PS.051455505 Variant Set Distributions Mapped Variants
General Structure Information 4l1u RTF1 crystal structure of human rtf1 plus3 domain in complex with spt5 ctr phosphopeptide 2.42Å AUTH A.D.WIER,M.K.MAYEKAR,A.HEROUX,K.M.ARNDT,A.P.VANDEMARKTITL STRUCTURAL BASIS FOR SPT5-MEDIATED RECRUITMENT OF THE PAF1TITL 2 COMPLEX TO CHROMATIN.REF PROC.NATL.ACAD.SCI.USA V. 110 17290 2013REFN ISSN 0027-8424PMID 24101474DOI 10.1073/PNAS.1314754110 Variant Set Distributions Mapped Variants
General Structure Information 2eko KAT5 solution structure of ruh-073, a pseudo chromo domain from human cdna -1.0Å AUTH A.Z.M.RUHUL MOMEN,H.HIROTA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RUH-073, A PSEUDO CHROMOTITL 2 DOMAIN FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l51 S100A16 solution structure of calcium bound s100a16 -1.0Å AUTH E.BABINI,I.BERTINI,V.BORSI,V.CALDERONE,X.HU,C.LUCHINAT,AUTH 2 G.PARIGITITL STRUCTURAL CHARACTERIZATION OF HUMAN S100A16, A LOW-AFFINITYTITL 2 CALCIUM BINDER.REF J.BIOL.INORG.CHEM. V. 16 243 2011REFN ISSN 0949-8257PMID 21046186DOI 10.1007/S00775-010-0721-3 Variant Set Distributions Mapped Variants