Assessment of Structural Intolerance and Durability
General Structure Information 2ymb MITD1 structures of mitd1 3.4Å AUTH M.A.HADDERS,M.AGROMAYOR,T.OBITA,O.PERISIC,A.CABALLE,M.KLOC,AUTH 2 M.H.LAMERS,R.L.WILLIAMS,J.MARTIN-SERRANOTITL ESCRT-III BINDING PROTEIN MITD1 IS INVOLVED IN CYTOKINESISTITL 2 AND HAS AN UNANTICIPATED PLD FOLD THAT BINDS MEMBRANES.REF PROC.NATL.ACAD.SCI.USA V. 109 17424 2012REFN ISSN 0027-8424PMID 23045692DOI 10.1073/PNAS.1206839109 Variant Set Distributions Mapped Variants
General Structure Information 1siq GCDH the crystal structure and mechanism of human glutaryl-coa dehydrogenase 2.1Å AUTH Z.FU,M.WANG,R.PASCHKE,K.S.RAO,F.E.FRERMAN,J.J.KIMTITL CRYSTAL STRUCTURES OF HUMAN GLUTARYL-COA DEHYDROGENASE WITHTITL 2 AND WITHOUT AN ALTERNATE SUBSTRATE: STRUCTURAL BASES OFTITL 3 DEHYDROGENATION AND DECARBOXYLATION REACTIONSREF BIOCHEMISTRY V. 43 9674 2004REFN ISSN 0006-2960PMID 15274622DOI 10.1021/BI049290C Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4lij FUBP1 crystal structure of a far upstream element (fuse) binding protein 1 (fubp1) from homo sapiens at 1.95 a resolution 1.8Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGYTITL CRYSTAL STRUCTURE OF A FAR UPSTREAM ELEMENT (FUSE) BINDINGTITL 2 PROTEIN 1 (FUBP1) FROM HOMO SAPIENS AT 1.95 […]
General Structure Information 4lec METTL21A human methyltransferase-like protein 21a 2.28Å AUTH H.ZENG,A.DONG,H.WUTITL THE CRYSTAL STRUCTURE OF HUMAN METHYLTRANSFERASE-LIKETITL 2 PROTEIN 21A IN COMPLEX WITH SAHREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1l0a TANK downstream regulator tank binds to the cd40 recognition site on traf3 2.9Å AUTH C.LI,C.Z.NI,M.L.HAVERT,E.CABEZAS,J.HE,D.KAISER,AUTH 2 J.C.REED,A.C.SATTERTHWAIT,G.CHENG,K.R.ELYTITL DOWNSTREAM REGULATOR TANK BINDS TO THE CD40TITL 2 RECOGNITION SITE ON TRAF3.REF STRUCTURE V. 10 403 2002REFN ISSN 0969-2126PMID 12005438DOI 10.1016/S0969-2126(02)00733-5 Variant Set Distributions Mapped Variants
General Structure Information 1xks NUP133 the crystal structure of the n-terminal domain of nup133 reveals a beta-propeller fold common to several nucleoporins 2.35Å AUTH I.C.BERKE,T.BOEHMER,G.BLOBEL,T.U.SCHWARTZTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF NUP133 DOMAINS REVEALSTITL 2 MODULAR BUILDING BLOCKS OF THE NUCLEAR PORE COMPLEX.REF J.CELL BIOL. V. 167 591 2004REFN ISSN 0021-9525PMID 15557116DOI 10.1083/JCB.200408109 Variant Set Distributions […]
General Structure Information 2l0a STAM solution nmr structure of signal transducing adapter molecule 1 stam-1 from homo sapiens, northeast structural genomics consortium target hr4479e -1.0Å AUTH Y.TANG,H.JANJUA,C.CICCOSANTI,R.SHASTRY,B.ROST,T.B.ACTON,AUTH 2 R.XIAO,J.K.EVERETT,G.T.MONTELIONE,C.H.ARROWSMITHTITL NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4479EREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jvz KHSRP solution nmr structure of the second and third kh domains of ksrp -1.0Å AUTH I.DIAZ-MORENO,D.HOLLINGWORTH,M.F.GARCIA-MAYORAL,AUTH 2 G.KELLY,S.MARTIN,C.Y.CHEN,A.RAMOSTITL SOLUTION NMR STRUCTURE OF THE SECOND AND THIRD KHTITL 2 DOMAINS OF KSRPREF TO BE PUBLISHED 2007REFN Variant Set Distributions Mapped Variants
General Structure Information 2ksn UBTD2 solution structure of the n-terminal domain of dc-ubp/ubtd2 -1.0Å AUTH A.SONG,C.ZHOU,X.GUAN,K.SZE,H.HUTITL SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DC-UBP/UBTD2TITL 2 AND ITS INTERACTION WITH UBIQUITINREF PROTEIN SCI. V. 19 1104 2010REFN ISSN 0961-8368PMID 20440844DOI 10.1002/PRO.386 Variant Set Distributions Mapped Variants
General Structure Information 1ury CYGB cytoglobin cavities 2.4Å AUTH D.DE SANCTIS,S.DEWILDE,A.PESCE,L.MOENS,P.ASCENZI,AUTH 2 T.HANKELN,T.BURMESTER,M.BOLOGNESITITL CYTOGLOBIN CAVITIESREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 316 1217 2004REFN ISSN 0006-291XPMID 15044115DOI 10.1016/J.BBRC.2004.03.007 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants