General Structure Information
| PDB ID | 1xks |
| HGNC Gene Label(s) | NUP133 |
| Structure Name | the crystal structure of the n-terminal domain of nup133 reveals a beta-propeller fold common to several nucleoporins |
| Resolution | 2.35Å |
| Reference | AUTH I.C.BERKE,T.BOEHMER,G.BLOBEL,T.U.SCHWARTZTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF NUP133 DOMAINS REVEALSTITL 2 MODULAR BUILDING BLOCKS OF THE NUCLEAR PORE COMPLEX.REF J.CELL BIOL. V. 167 591 2004REFN ISSN 0021-9525PMID 15557116DOI 10.1083/JCB.200408109 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 374 |
| Number Of SNVs | 94 |
| Number Of Permutations | 44605 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.014 |
| p-value | 0.308 |
COSMIC
| Number Of Residues | 374 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1577 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.2 |
| p-value | 0.239 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 94 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.425 |
| p-value | 0.975 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
