General Structure Information
| PDB ID | 4lec |
| HGNC Gene Label(s) | METTL21A |
| Structure Name | human methyltransferase-like protein 21a |
| Resolution | 2.28Å |
| Reference | AUTH H.ZENG,A.DONG,H.WUTITL THE CRYSTAL STRUCTURE OF HUMAN METHYLTRANSFERASE-LIKETITL 2 PROTEIN 21A IN COMPLEX WITH SAHREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 202 |
| Number Of SNVs | 53 |
| Number Of Permutations | 6151 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.147 |
| p-value | 0.052 |
COSMIC
| Number Of Residues | 202 |
| Number Of SNVs | 3 |
| Number Of Permutations | 162 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.667 |
| p-value | 0.116 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.52 |
| p-value | 0.215 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
