Assessment of Structural Intolerance and Durability
General Structure Information 1y96 GEMIN7 crystal structure of the gemin6/gemin7 heterodimer from the human smn complex 2.0Å AUTH Y.MA,J.DOSTIE,G.DREYFUSS,G.D.VAN DUYNETITL THE GEMIN6-GEMIN7 HETERODIMER FROM THE SURVIVAL OFTITL 2 MOTOR NEURONS COMPLEX HAS AN SM PROTEIN-LIKETITL 3 STRUCTURE.REF STRUCTURE V. 13 883 2005REFN ISSN 0969-2126PMID 15939020DOI 10.1016/J.STR.2005.03.014 Variant Set Distributions Mapped Variants
General Structure Information 4bx9 VPS16 human vps33a in complex with a fragment of human vps16 2.6Å AUTH S.C.GRAHAM,L.WARTOSCH,S.R.GRAY,E.J.SCOURFIELD,J.E.DEANE,AUTH 2 J.P.LUZIO,D.J.OWENTITL STRUCTURAL BASIS OF VPS33A RECRUITMENT TO THE HUMAN HOPSTITL 2 COMPLEX BY VPS16.REF PROC.NATL.ACAD.SCI.USA V. 110 13345 2013REFN ISSN 0027-8424PMID 23901104DOI 10.1073/PNAS.1307074110 Variant Set Distributions Mapped Variants
General Structure Information 3d2n MBNL1 crystal structure of mbnl1 tandem zinc finger 1 and 2 domain 2.7Å AUTH M.TEPLOVA,D.J.PATELTITL STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY THETITL 2 ALTERNATIVE-SPLICING REGULATOR MUSCLEBLIND-LIKETITL 3 MBNL1.REF NAT.STRUCT.MOL.BIOL. V. 15 1343 2008REFN ISSN 1545-9993PMID 19043415DOI 10.1038/NSMB.1519 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 2cpd A1CF solution structure of the rna recognition motif of human apobec-1 complementation factor, acf -1.0Å AUTH T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF OFTITL 2 HUMAN APOBEC-1 COMPLEMENTATION FACTOR, ACFREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wel RBM12 solution structure of rna binding domain in np_006038 -1.0Å AUTH T.SOMEYA,Y.MUTO,T.NAGATA,S.SUZUKI,M.INOUE,T.KIGAWA,AUTH 2 T.TERADA,M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 NP_006038REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3k6g TERF2IP crystal structure of rap1 and trf2 complex 1.95Å AUTH Y.CHEN,R.RAI,Z.R.ZHOU,J.KANOH,C.RIBEYRE,Y.YANG,H.ZHENG,AUTH 2 P.DAMAY,F.WANG,H.TSUJII,Y.HIRAOKA,D.SHORE,H.Y.HU,S.CHANG,AUTH 3 M.LEITITL A CONSERVED MOTIF WITHIN RAP1 HAS DIVERSIFIED ROLES INTITL 2 TELOMERE PROTECTION AND REGULATION IN DIFFERENT ORGANISMS.REF NAT.STRUCT.MOL.BIOL. V. 18 213 2011REFN ISSN 1545-9993PMID 21217703DOI 10.1038/NSMB.1974 Variant Set Distributions Mapped Variants
General Structure Information 3rwr NHEJ1 crystal structure of the human xrcc4-xlf complex 3.94Å AUTH N.S.ANDRES,C.WYMAN,M.MODESTI,M.S.JUNOPTITL STRUCTURE OF HUMAN XLF-XRCC4: ASSEMBLY OF A FUNCTIONAL DNATITL 2 REPAIR COMPLEXREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4l8t MYO5C structure of the cargo binding domain from human myosin vc 2.95Å AUTH A.F.NASCIMENTO,D.M.TRINDADE,C.C.TONOLI,P.O.DE GIUSEPPE,AUTH 2 L.H.ASSIS,R.V.HONORATO,P.S.DE OLIVEIRA,P.MAHAJAN,AUTH 3 N.A.BURGESS-BROWN,F.VON DELFT,R.E.LARSON,M.T.MURAKAMITITL STRUCTURAL INSIGHTS INTO FUNCTIONAL OVERLAPPING ANDTITL 2 DIFFERENTIATION AMONG MYOSIN V MOTORS.REF J.BIOL.CHEM. V. 288 34131 2013REFN ISSN 0021-9258PMID 24097982DOI 10.1074/JBC.M113.507202 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3toa KAT8 human mof crystal structure with active site lysine partially acetylated 3.0Å AUTH H.YUAN,D.ROSSETTO,H.MELLERT,W.DANG,M.SRINIVASAN,J.JOHNSON,AUTH 2 S.HODAWADEKAR,E.C.DING,K.SPEICHER,N.ABSHIRU,R.PERRY,J.WU,AUTH 3 C.YANG,Y.G.ZHENG,D.W.SPEICHER,P.THIBAULT,A.VERREAULT,AUTH 4 F.B.JOHNSON,S.L.BERGER,R.STERNGLANZ,S.B.MCMAHON,J.COTE,AUTH 5 R.MARMORSTEINTITL MYST PROTEIN ACETYLTRANSFERASE ACTIVITY REQUIRES ACTIVE SITETITL 2 LYSINE AUTOACETYLATION.REF EMBO J. V. 31 58 2011REFN ISSN 0261-4189PMID 22020126DOI 10.1038/EMBOJ.2011.382 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3hve GAN structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: gigaxoninbtb/3-box 2.8Å AUTH M.ZHUANG,M.F.CALABRESE,J.LIU,M.B.WADDELL,A.NOURSE,AUTH 2 M.HAMMEL,D.J.MILLER,H.WALDEN,D.M.DUDA,S.N.SEYEDIN,AUTH 3 T.HOGGARD,J.W.HARPER,K.P.WHITE,B.A.SCHULMANTITL STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTSTITL 2 INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITINTITL 3 LIGASES.REF MOL.CELL V. 36 39 2009REFN ISSN 1097-2765PMID 19818708DOI 10.1016/J.MOLCEL.2009.09.022 Variant Set Distributions Ripley’s K Analysis Plots […]