General Structure Information
| PDB ID | 4l8t |
| HGNC Gene Label(s) | MYO5C |
| Structure Name | structure of the cargo binding domain from human myosin vc |
| Resolution | 2.95Å |
| Reference | AUTH A.F.NASCIMENTO,D.M.TRINDADE,C.C.TONOLI,P.O.DE GIUSEPPE,AUTH 2 L.H.ASSIS,R.V.HONORATO,P.S.DE OLIVEIRA,P.MAHAJAN,AUTH 3 N.A.BURGESS-BROWN,F.VON DELFT,R.E.LARSON,M.T.MURAKAMITITL STRUCTURAL INSIGHTS INTO FUNCTIONAL OVERLAPPING ANDTITL 2 DIFFERENTIATION AMONG MYOSIN V MOTORS.REF J.BIOL.CHEM. V. 288 34131 2013REFN ISSN 0021-9258PMID 24097982DOI 10.1074/JBC.M113.507202 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 363 |
| Number Of SNVs | 94 |
| Number Of Permutations | 55651 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.04 |
| p-value | 0.998 |
COSMIC
| Number Of Residues | 363 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2377 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.133 |
| p-value | 0.77 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 94 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.171 |
| p-value | 0.972 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
