General Structure Information
| PDB ID | 3toa |
| HGNC Gene Label(s) | KAT8 |
| Structure Name | human mof crystal structure with active site lysine partially acetylated |
| Resolution | 3.0Å |
| Reference | AUTH H.YUAN,D.ROSSETTO,H.MELLERT,W.DANG,M.SRINIVASAN,J.JOHNSON,AUTH 2 S.HODAWADEKAR,E.C.DING,K.SPEICHER,N.ABSHIRU,R.PERRY,J.WU,AUTH 3 C.YANG,Y.G.ZHENG,D.W.SPEICHER,P.THIBAULT,A.VERREAULT,AUTH 4 F.B.JOHNSON,S.L.BERGER,R.STERNGLANZ,S.B.MCMAHON,J.COTE,AUTH 5 R.MARMORSTEINTITL MYST PROTEIN ACETYLTRANSFERASE ACTIVITY REQUIRES ACTIVE SITETITL 2 LYSINE AUTOACETYLATION.REF EMBO J. V. 31 58 2011REFN ISSN 0261-4189PMID 22020126DOI 10.1038/EMBOJ.2011.382 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 265 |
| Number Of SNVs | 37 |
| Number Of Permutations | 28184 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.018 |
| p-value | 0.946 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
