General Structure Information 3a8w PRKCI crystal structure of pkciota kinase domain 2.1Å AUTH T.TAKIMURA,K.KAMATA,K.FUKASAWA,H.OHSAWA,H.KOMATANI,AUTH 2 T.YOSHIZUMI,I.TAKAHASHI,H.KOTANI,Y.IWASAWATITL STRUCTURES OF THE PKC-IOTA KINASE DOMAIN IN ITS ATP-BOUNDTITL 2 AND APO FORMS REVEAL DEFINED STRUCTURES OF RESIDUES 533-551TITL 3 IN THE C-TERMINAL TAIL AND THEIR ROLES IN ATP BINDINGREF ACTA CRYSTALLOGR.,SECT.D V. 66 577 2010REFN ISSN 0907-4449PMID 20445233DOI […]
General Structure Information 4fu4 MMP13 human collagenase 3 (mmp-13) with peptide from pro-domain 2.85Å AUTH E.A.STURA,R.VISSE,P.CUNIASSE,V.DIVE,H.NAGASETITL CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN COLLAGENASE 3TITL 2 (MMP-13) WITH PEPTIDES IN THE ACTIVE SITE DEFINES EXOSITESTITL 3 IN THE CATALYTIC DOMAIN.REF FASEB J. V. 27 4395 2013REFN ISSN 0892-6638PMID 23913860DOI 10.1096/FJ.13-233601 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4fu4 MMP13 human collagenase 3 (mmp-13) with peptide from pro-domain 2.85Å AUTH E.A.STURA,R.VISSE,P.CUNIASSE,V.DIVE,H.NAGASETITL CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN COLLAGENASE 3TITL 2 (MMP-13) WITH PEPTIDES IN THE ACTIVE SITE DEFINES EXOSITESTITL 3 IN THE CATALYTIC DOMAIN.REF FASEB J. V. 27 4395 2013REFN ISSN 0892-6638PMID 23913860DOI 10.1096/FJ.13-233601 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3uom CASQ1 ca2+ complex of human skeletal calsequestrin 2.02Å AUTH E.J.SANCHEZ,K.M.LEWIS,B.R.DANNA,C.KANGTITL HIGH-CAPACITY CA2+ BINDING OF HUMAN SKELETAL CALSEQUESTRIN.REF J.BIOL.CHEM. V. 287 11592 2012REFN ISSN 0021-9258PMID 22337878DOI 10.1074/JBC.M111.335075 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3evs GDF5 crystal structure of the gdf-5:bmp receptor ib complex. 2.1Å AUTH A.KOTZSCH,J.NICKEL,A.SEHER,W.SEBALD,T.D.MULLERTITL CRYSTAL STRUCTURE ANALYSIS REVEALS A SPRING-LOADED LATCH ASTITL 2 MOLECULAR MECHANISM FOR GDF-5-TYPE I RECEPTOR SPECIFICITY.REF EMBO J. V. 28 937 2009REFN ISSN 0261-4189PMID 19229295DOI 10.1038/EMBOJ.2009.37 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4cga CHKA human choline kinase a1 in complex with compound 5 1.74Å AUTH B.RUBIO-RUIZ,A.FIGUEROLA-CONCHAS,J.RAMOS-TORRECILLAS,AUTH 2 F.CAPITAN-CANADAS,P.RIOS-MARCO,M.P.CARRASCO,M.A.GALLO,AUTH 3 A.ESPINOSA,C.MARCO,C.CONCEPCION,A.ENTRENA-GUADIX,AUTH 4 R.HURTADO-GUERRERO,A.CONEJO-GARCIATITL DISCOVERY OF A NEW BINDING SITE ON HUMAN CHOLINE KINASE A1:TITL 2 DESIGN, SYNTHESIS, CRYSTALLOGRAPHIC STUDIES AND BIOLOGICALTITL 3 EVALUATION OF ASYMMETRICAL BISPYRIDINIUM DERIVATIVESREF J.MED.CHEM. V. 57 507 2014REFN ISSN 0022-2623PMID 24387243DOI […]
General Structure Information 2m74 FBN1 1h, 13c and 15n assignments of the four n-terminal domains of human fibrillin-1 -1.0Å AUTH D.A.YADIN,I.B.ROBERTSON,J.MCNAUGHT-DAVIS,P.EVANS,D.STODDART,AUTH 2 P.A.HANDFORD,S.A.JENSEN,C.REDFIELDTITL STRUCTURE OF THE FIBRILLIN-1 N-TERMINAL DOMAINS SUGGESTSTITL 2 THAT HEPARAN SULFATE REGULATES THE EARLY STAGES OFTITL 3 MICROFIBRIL ASSEMBLY.REF STRUCTURE V. 21 1743 2013REFN ISSN 0969-2126PMID 24035709DOI 10.1016/J.STR.2013.08.004 Variant Set Distributions Ripley’s […]
General Structure Information 1apj FBN1 nmr study of the transforming growth factor beta binding protein-like domain (tb module/8-cys domain), nmr, 21 structures -1.0Å AUTH X.YUAN,A.K.DOWNING,V.KNOTT,P.A.HANDFORDTITL SOLUTION STRUCTURE OF THE TRANSFORMING GROWTHTITL 2 FACTOR BETA-BINDING PROTEIN-LIKE MODULE, A DOMAINTITL 3 ASSOCIATED WITH MATRIX FIBRILS.REF EMBO J. V. 16 6659 1997REFN ISSN 0261-4189PMID 9362480DOI 10.1093/EMBOJ/16.22.6659 Variant Set […]
General Structure Information 1qqg IRS1 crystal structure of the ph-ptb targeting region of irs-1 2.3Å AUTH S.DHE-PAGANON,E.A.OTTINGER,R.T.NOLTE,M.J.ECK,AUTH 2 S.E.SHOELSONTITL CRYSTAL STRUCTURE OF THE PLECKSTRINTITL 2 HOMOLOGY-PHOSPHOTYROSINE BINDING (PH-PTB)TITL 3 TARGETING REGION OF INSULIN RECEPTOR SUBSTRATE 1.REF PROC.NATL.ACAD.SCI.USA V. 96 8378 1999REFN ISSN 0027-8424PMID 10411883DOI 10.1073/PNAS.96.15.8378 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1i8l CD80 human b7-1/ctla-4 co-stimulatory complex 3.0Å AUTH C.C.STAMPER,Y.ZHANG,J.F.TOBIN,D.V.ERBE,S.IKEMIZU,S.J.DAVIS,AUTH 2 M.L.STAHL,J.SEEHRA,W.S.SOMERS,L.MOSYAKTITL CRYSTAL STRUCTURE OF THE B7-1/CTLA-4 COMPLEX THAT INHIBITSTITL 2 HUMAN IMMUNE RESPONSES.REF NATURE V. 410 608 2001REFN ISSN 0028-0836PMID 11279502DOI 10.1038/35069118 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants