Assessment of Structural Intolerance and Durability
General Structure Information 3r27 HNRNPL crystal structure of the first rrm domain of heterogeneous nuclear ribonucleoprotein l (hnrnp l) 2.04Å AUTH W.ZHANG,Y.LIU,F.ZENG,L.NIU,M.TENG,X.LITITL CRYSTAL STRUCTURE OF THE FIRST RRM DOMAIN OF HETEROGENEOUSTITL 2 NUCLEAR RIBONUCLEOPROTEIN L (HNRNP L)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2z6k RPA2 crystal structure of full-length human rpa14/32 heterodimer 3.0Å AUTH X.DENG,J.E.HABEL,V.KABALEESWARAN,E.H.SNELL,AUTH 2 M.S.WOLD,G.E.BORGSTAHLTITL STRUCTURE OF THE FULL-LENGTH HUMAN RPA14/32TITL 2 COMPLEX GIVES INSIGHTS INTO THE MECHANISM OF DNATITL 3 BINDING AND COMPLEX FORMATIONREF J.MOL.BIOL. V. 374 865 2007REFN ISSN 0022-2836PMID 17976647DOI 10.1016/J.JMB.2007.09.074 Variant Set Distributions Mapped Variants
General Structure Information 2krr NCL solution structure of the rbd1,2 domains from human nucleolin -1.0Å AUTH S.ARUMUGAM,M.C.MILLER,J.MALIEKAL,P.J.BATES,J.O.TRENT,AUTH 2 A.N.LANETITL SOLUTION STRUCTURE OF THE RBD1,2 DOMAINS FROM HUMANTITL 2 NUCLEOLIN.REF J.BIOMOL.NMR V. 47 79 2010REFN ISSN 0925-2738PMID 20376532DOI 10.1007/S10858-010-9412-1 Variant Set Distributions Mapped Variants
General Structure Information 3dzu RXRA intact ppar gamma – rxr alpha nuclear receptor complex on dna bound with bvt.13, 9-cis retinoic acid and ncoa2 peptide 3.2Å AUTH V.CHANDRA,P.HUANG,Y.HAMURO,S.RAGHURAM,Y.WANG,T.P.BURRIS,AUTH 2 F.RASTINEJADTITL STRUCTURE OF THE INTACT PPAR-GAMMA-RXR- NUCLEAR RECEPTORTITL 2 COMPLEX ON DNA.REF NATURE V. 456 350 2008REFN ISSN 0028-0836PMID 19043829DOI 10.1038/NATURE07413 Variant Set Distributions Ripley’s K […]
General Structure Information 3lhr ZNF24 crystal structure of the scan domain from human znf24 1.9Å AUTH B.F.VOLKMAN,F.C.PETERSON,C.A.BINGMAN,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF THE SCAN DOMAIN FROM HUMAN ZNF24REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jvn PARP1 domain c of human parp-1 -1.0Å AUTH Z.TAO,P.GAO,D.W.HOFFMAN,H.W.LIUTITL DOMAIN C OF HUMAN POLY(ADP-RIBOSE) POLYMERASE-1 IS IMPORTANTTITL 2 FOR ENZYME ACTIVITY AND CONTAINS A NOVEL ZINC-RIBBON MOTIF.REF BIOCHEMISTRY V. 47 5804 2008REFN ISSN 0006-2960PMID 18452307DOI 10.1021/BI800018A Variant Set Distributions Mapped Variants
General Structure Information 4dqm RARA revealing a marine natural product as a novel agonist for retinoic acid receptors with a unique binding mode and antitumor activity 2.75Å AUTH S.WANG,Z.WANG,S.LIN,W.ZHENG,R.WANG,S.JIN,J.CHEN,L.JIN,Y.LITITL REVEALING A NATURAL MARINE PRODUCT AS A NOVEL AGONIST FORTITL 2 RETINOIC ACID RECEPTORS WITH A UNIQUE BINDING MODE ANDTITL 3 INHIBITORY EFFECTS ON CANCER CELLS.REF […]
General Structure Information 3b97 ENO1 crystal structure of human enolase 1 2.2Å AUTH H.J.KANG,S.K.JUNG,S.J.KIM,S.J.CHUNGTITL STRUCTURE OF HUMAN ALPHA-ENOLASE (HENO1), ATITL 2 MULTIFUNCTIONAL GLYCOLYTIC ENZYME.REF ACTA CRYSTALLOGR.,SECT.D V. 64 651 2008REFN ISSN 0907-4449PMID 18560153DOI 10.1107/S0907444908008561 Variant Set Distributions Mapped Variants
General Structure Information 3tzd HIST1H1E crystal structure of the complex of human chromobox homolog 3 (cbx3) 1.81Å AUTH J.RUAN,H.OUYANG,M.F.AMAYA,M.RAVICHANDRAN,P.LOPPNAU,J.MIN,AUTH 2 J.ZANGTITL STRUCTURAL BASIS OF THE CHROMODOMAIN OF CBX3 BOUND TOTITL 2 METHYLATED PEPTIDES FROM HISTONE H1 AND G9A.REF PLOS ONE V. 7 35376 2012REFN ESSN 1932-6203PMID 22514736DOI 10.1371/JOURNAL.PONE.0035376 Variant Set Distributions Mapped Variants
General Structure Information 3d24 ESRRA crystal structure of ligand-binding domain of estrogen- related receptor alpha (erralpha) in complex with the peroxisome proliferators-activated receptor coactivator- 1alpha box3 peptide (pgc-1alpha) 2.11Å AUTH H.GRESCHIK,M.ALTHAGE,R.FLAIG,Y.SATO,V.CHAVANT,AUTH 2 C.PELUSO-ILTIS,L.CHOULIER,P.CRONET,N.ROCHEL,AUTH 3 R.SCHULE,P.E.STROMSTEDT,D.MORASTITL COMMUNICATION BETWEEN THE ERR{ALPHA} HOMODIMERTITL 2 INTERFACE AND THE PGC-1{ALPHA} BINDING SURFACE VIATITL 3 THE HELIX 8-9 LOOP.REF J.BIOL.CHEM. V. […]