4IU7.B | ESR1

General Structure Information 4iu7 ESR1 crystal structure of the estrogen receptor alpha ligand-binding domain in complex with constrained way-derivative, 2b 2.29Å AUTH S.SRINIVASAN,J.C.NWACHUKWU,A.A.PARENT,V.CAVETT,J.NOWAK,AUTH 2 T.S.HUGHES,D.J.KOJETIN,J.A.KATZENELLENBOGEN,K.W.NETTLESTITL LIGAND BINDING DYNAMICS REWIRE CELLULAR SIGNALING VIATITL 2 ESTROGEN RECEPTOR-ALPHAREF NAT.CHEM.BIOL. V. 9 326 2013REFN ISSN 1552-4450PMID 23524984DOI 10.1038/NCHEMBIO.1214 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]

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3FY7.B | CLIC3

General Structure Information 3fy7 CLIC3 crystal structure of homo sapiens clic3 1.95Å AUTH D.R.LITTLER,L.J.BROWN,S.N.BREIT,A.PERRAKIS,P.M.G.CURMITITL STRUCTURE OF HUMAN CLIC3 AT 2 A RESOLUTIONREF PROTEINS V. 78 1594 2010REFN ISSN 0887-3585PMID 20146363DOI 10.1002/PROT.22675 Variant Set Distributions Mapped Variants

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2VOO.A | SSB

General Structure Information 2voo SSB crystal structure of n-terminal domains of human la protein complexed with rna oligomer uuuuuuuu 1.8Å AUTH O.KOTIK-KOGAN,E.R.VALENTINE,D.SANFELICE,M.R.CONTE,AUTH 2 S.CURRYTITL STRUCTURAL ANALYSIS REVEALS CONFORMATIONALTITL 2 PLASTICITY IN THE RECOGNITION OF RNA 3 ENDS BYTITL 3 THE HUMAN LA PROTEIN.REF STRUCTURE V. 16 852 2008REFN ISSN 0969-2126PMID 18547518DOI 10.1016/J.STR.2008.02.021 Variant Set Distributions […]

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3E7C.A | NR3C1

General Structure Information 3e7c NR3C1 glucocorticoid receptor lbd bound to gsk866 2.15Å AUTH K.P.MADAUSS,R.K.BLEDSOE,I.MCLAY,E.L.STEWART,I.J.UINGS,AUTH 2 G.WEINGARTEN,S.P.WILLIAMSTITL THE FIRST X-RAY CRYSTAL STRUCTURE OF THE GLUCOCORTICOIDTITL 2 RECEPTOR BOUND TO A NON-STEROIDAL AGONIST.REF BIOORG.MED.CHEM.LETT. V. 18 6097 2008REFN ISSN 0960-894XPMID 18952422DOI 10.1016/J.BMCL.2008.10.021 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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3I6W.H | CHEK2

General Structure Information 3i6w CHEK2 structure and activation mechanism of the chk2 dna-damage checkpoint kinase 3.25Å AUTH Z.CAI,N.H.CHEHAB,N.P.PAVLETICHTITL STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA DAMAGETITL 2 CHECKPOINT KINASE.REF MOL.CELL V. 35 818 2009REFN ISSN 1097-2765PMID 19782031DOI 10.1016/J.MOLCEL.2009.09.007 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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3LM0.A | STK17B

General Structure Information 3lm0 STK17B crystal structure of human serine/threonine kinase 17b (stk17b) 2.35Å Variant Set Distributions Mapped Variants

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2ZNE.B | PDCD6

General Structure Information 2zne PDCD6 crystal structure of zn2+-bound form of des3-23alg-2 complexed with alix abs peptide 2.2Å AUTH H.SUZUKI,M.KAWASAKI,T.INUZUKA,M.OKUMURA,T.KAKIUCHI,AUTH 2 H.SHIBATA,S.WAKATSUKI,M.MAKITITL STRUCTURAL BASIS FOR CA(2+)-DEPENDENT FORMATION OFTITL 2 ALG-2/ALIX PEPTIDE COMPLEX: CA(2+)/EF3-DRIVENTITL 3 ARGININE SWITCH MECHANISMREF STRUCTURE V. 16 1562 2008REFN ISSN 0969-2126PMID 18940611DOI 10.1016/J.STR.2008.07.012 Variant Set Distributions Mapped Variants

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4MBB.A | DUSP11

General Structure Information 4mbb DUSP11 cubic crystal form of pir1 dual specificity phosphatase core 1.85Å AUTH R.S.SANKHALA,R.K.LOKAREDDY,G.CINGOLANITITL STRUCTURE OF HUMAN PIR1, AN ATYPICAL DUAL-SPECIFICITYTITL 2 PHOSPHATASE.REF BIOCHEMISTRY V. 53 862 2014REFN ISSN 0006-2960PMID 24447265DOI 10.1021/BI401240X Variant Set Distributions Mapped Variants

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2KDP.A | SAP30

General Structure Information 2kdp SAP30 solution structure of the sap30 zinc finger motif -1.0Å AUTH Y.HE,R.IMHOFF,A.SAHU,I.RADHAKRISHNANTITL SOLUTION STRUCTURE OF A NOVEL ZINC FINGER MOTIF INTITL 2 THE SAP30 POLYPEPTIDE OF THE SIN3 COREPRESSORTITL 3 COMPLEX AND ITS POTENTIAL ROLE IN NUCLEIC ACIDTITL 4 RECOGNITIONREF NUCLEIC ACIDS RES. V. 37 2142 2009REFN ISSN 0305-1048PMID 19223330DOI 10.1093/NAR/GKP051 […]

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3A03.A | TLX2

General Structure Information 3a03 TLX2 crystal structure of hox11l1 homeodomain 1.54Å AUTH K.MIYAZONO,Y.ZHI,Y.TAKAMURA,K.NAGATA,K.SAIGO,T.KOJIMA,AUTH 2 M.TANOKURATITL COOPERATIVE DNA-BINDING AND SEQUENCE-RECOGNITION MECHANISMTITL 2 OF ARISTALESS AND CLAWLESSREF EMBO J. V. 29 1613 2010REFN ISSN 0261-4189PMID 20389279DOI 10.1038/EMBOJ.2010.53 Variant Set Distributions Mapped Variants

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