General Structure Information
| PDB ID | 3dzu |
| HGNC Gene Label(s) | RXRA |
| Structure Name | intact ppar gamma – rxr alpha nuclear receptor complex on dna bound with bvt.13, 9-cis retinoic acid and ncoa2 peptide |
| Resolution | 3.2Å |
| Reference | AUTH V.CHANDRA,P.HUANG,Y.HAMURO,S.RAGHURAM,Y.WANG,T.P.BURRIS,AUTH 2 F.RASTINEJADTITL STRUCTURE OF THE INTACT PPAR-GAMMA-RXR- NUCLEAR RECEPTORTITL 2 COMPLEX ON DNA.REF NATURE V. 456 350 2008REFN ISSN 0028-0836PMID 19043829DOI 10.1038/NATURE07413 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 289 |
| Number Of SNVs | 45 |
| Number Of Permutations | 37439 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.042 |
| p-value | 0.525 |
COSMIC
| Number Of Residues | 289 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1218 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.095 |
| p-value | 0.509 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 45 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.052 |
| p-value | 0.561 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
