4IE5.A | FTO

General Structure Information 4ie5 FTO crystal structure of the human fat mass and obesity associated protein (fto) in complex with n-[(3-hydroxypyridin-2-yl)carbonyl]glycine (md6) 1.95Å AUTH W.S.AIK,M.DEMETRIADES,M.K.K.HAMDAN,E.A.L.BAGG,K.K.YEOH,AUTH 2 C.LEJEUNE,Z.ZHANG,M.A.MCDONOUGH,C.J.SCHOFIELDTITL STRUCTURAL BASIS FOR INHIBITION OF THE FAT MASS AND OBESITYTITL 2 ASSOCIATED PROTEIN (FTO)REF J.MED.CHEM. V. 56 3680 2013REFN ISSN 0022-2623PMID 23547775DOI 10.1021/JM400193D Variant Set Distributions Mapped Variants

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2MKF.A | UIMC1

General Structure Information 2mkf UIMC1 solution structure of the e81 deletion mutant of the tandem uims of rap80 -1.0Å AUTH ANAMIKA,C.J.MARKIN,M.K.ROUT,L.SPYRACOPOULOSTITL MOLECULAR BASIS FOR IMPAIRED DNA DAMAGE RESPONSE FUNCTIONTITL 2 ASSOCIATED WITH THE RAP80 DELTA E81 DEFECT.REF J.BIOL.CHEM. V. 289 12852 2014REFN ISSN 0021-9258PMID 24627472DOI 10.1074/JBC.M113.538280 Variant Set Distributions Mapped Variants

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2R2J.A | ERP44

General Structure Information 2r2j ERP44 crystal structure of human erp44 2.6Å AUTH L.K.WANG,L.WANG,S.VAVASSORI,S.J.LI,H.KE,T.ANELLI,M.DEGANO,AUTH 2 R.RONZONI,R.SITIA,F.SUN,C.C.WANGTITL CRYSTAL STRUCTURE OF HUMAN ERP44 SHOWS A DYNAMIC FUNCTIONALTITL 2 MODULATION BY ITS CARBOXY-TERMINAL TAIL.REF EMBO REP. 2008REFN ESSN 1469-3178PMID 18552768DOI 10.1038/EMBOR.2008.88 Variant Set Distributions Mapped Variants

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2L9S.A | PHF12

General Structure Information 2l9s PHF12 solution structure of pf1 sid1-msin3a pah2 complex -1.0Å AUTH G.S.KUMAR,T.XIE,Y.ZHANG,I.RADHAKRISHNANTITL SOLUTION STRUCTURE OF THE MSIN3A PAH2-PF1 SID1 COMPLEX: ATITL 2 MAD1/MXD1-LIKE INTERACTION DISRUPTED BY MRG15 IN THETITL 3 RPD3S/SIN3S COMPLEX.REF J.MOL.BIOL. V. 408 987 2011REFN ISSN 0022-2836PMID 21440557DOI 10.1016/J.JMB.2011.03.043 Variant Set Distributions Mapped Variants

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2CQD.A | RBM38

General Structure Information 2cqd RBM38 solution structure of the rna recognition motif in rna- binding region containing protein 1 -1.0Å AUTH T.SOMEYA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF INTITL 2 RNA-BINDING REGION CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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1S18.A | CANT1

General Structure Information 1s18 CANT1 structure and protein design of human apyrase 1.7Å AUTH J.DAI,J.LIU,Y.DENG,T.M.SMITH,M.LUTITL STRUCTURE AND PROTEIN DESIGN OF A HUMAN PLATELETTITL 2 FUNCTION INHIBITOR.REF CELL(CAMBRIDGE,MASS.) V. 116 649 2004REFN ISSN 0092-8674PMID 15006348DOI 10.1016/S0092-8674(04)00172-2 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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3THT.A | ALKBH8

General Structure Information 3tht ALKBH8 crystal structure and rna binding properties of the rrm/alkb domains in human abh8, an enzyme catalyzing trna hypermodification, northeast structural genomics consortium target hr5601b 3.01Å AUTH C.PASTORE,I.TOPALIDOU,F.FOROUHAR,A.C.YAN,M.LEVY,J.F.HUNTTITL CRYSTAL STRUCTURE AND RNA BINDING PROPERTIES OF THE RNATITL 2 RECOGNITION MOTIF (RRM) AND ALKB DOMAINS IN HUMAN ALKBTITL 3 HOMOLOG 8 (ABH8), […]

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1XR0.B | FRS2

General Structure Information 1xr0 FRS2 structural basis of snt ptb domain interactions with distinct neurotrophic receptors -1.0Å AUTH C.DHALLUIN,K.S.YAN,O.PLOTNIKOVA,K.W.LEE,L.ZENG,AUTH 2 M.KUTI,S.MUJTABA,M.P.GOLDFARB,M.-M.ZHOUTITL STRUCTURAL BASIS OF SNT PTB DOMAIN INTERACTIONSTITL 2 WITH DISTINCT NEUROTROPHIC RECEPTORSREF MOL.CELL V. 6 921 2000REFN ISSN 1097-2765PMID 11090629DOI 10.1016/S1097-2765(05)00087-0 Variant Set Distributions Mapped Variants

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3DDT.A | TRIM63

General Structure Information 3ddt TRIM63 crystal structure of the b2 box from murf1 in dimeric state 1.9Å AUTH M.MROSEK,S.MEIER,Z.UCURUM-FOTIADIS,E.VON CASTELMUR,AUTH 2 E.HEDBOM,A.LUSTIG,S.GRZESIEK,D.LABEIT,S.LABEIT,AUTH 3 O.MAYANSTITL STRUCTURAL ANALYSIS OF B-BOX 2 FROM MURF1:TITL 2 IDENTIFICATION OF A NOVEL SELF-ASSOCIATION PATTERNTITL 3 IN A RING-LIKE FOLDREF BIOCHEMISTRY V. 47 10722 2008REFN ISSN 0006-2960PMID 18795805DOI 10.1021/BI800733Z Variant Set Distributions […]

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3LE4.A | DGCR8

General Structure Information 3le4 DGCR8 crystal structure of the dgcr8 dimerization domain 1.7Å AUTH R.SENTURIA,M.FALLER,S.YIN,J.A.LOO,D.CASCIO,M.R.SAWAYA,AUTH 2 D.HWANG,R.T.CLUBB,F.GUOTITL STRUCTURE OF THE DIMERIZATION DOMAIN OF DIGEORGE CRITICALTITL 2 REGION 8REF PROTEIN SCI. V. 19 1354 2010REFN ISSN 0961-8368PMID 20506313DOI 10.1002/PRO.414 Variant Set Distributions Mapped Variants

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