Assessment of Structural Intolerance and Durability
General Structure Information 2dmp ZHX2 solution structure of the third homeobox domain of zinc fingers and homeoboxes protein 2 -1.0Å AUTH S.OHNISHI,A.SASAGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD HOMEOBOX DOMAIN OFTITL 2 ZINC FINGERS AND HOMEOBOXES PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1t8u HS3ST3A1 crystal structure of human 3-o-sulfotransferase-3 with bound pap and tetrasaccharide substrate 1.95Å AUTH A.F.MOON,S.C.EDAVETTAL,J.M.KRAHN,E.M.MUNOZ,M.NEGISHI,AUTH 2 R.J.LINHARDT,J.LIU,L.C.PEDERSENTITL STRUCTURAL ANALYSIS OF THE SULFOTRANSFERASETITL 2 (3-O-SULFOTRANSFERASE ISOFORM 3) INVOLVED IN THETITL 3 BIOSYNTHESIS OF AN ENTRY RECEPTOR FOR HERPES SIMPLEX VIRUS 1REF J.BIOL.CHEM. V. 279 45185 2004REFN ISSN 0021-9258PMID 15304505DOI 10.1074/JBC.M405013200 Variant Set […]
General Structure Information 2ch0 LEMD3 solution structure of the human man1 c-terminal domain (residues 655-775) -1.0Å AUTH S.CAPUTO,J.COUPRIE,I.DUBAND-GOULET,F.LIN,S.BRAUD,AUTH 2 M.GONDRY,H.J.WORMAN,B.GILQUIN,S.ZINN-JUSTINTITL THE CARBOXYL-TERMINAL NUCLEOPLASMIC REGION OF MAN1TITL 2 EXHIBITS A DNA BINDING WINGED HELIX DOMAIN.REF J.BIOL.CHEM. V. 281 18208 2006REFN ISSN 0021-9258PMID 16648637DOI 10.1074/JBC.M601980200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3ue2 PUF60 crystal structure of a rna binding domain of poly-u binding splicing factor 60kda (puf60) from homo sapiens at 1.23 a resolution 1.23Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGYTITL CRYSTAL STRUCTURE OF A RNA BINDING DOMAIN OF POLY-U BINDINGTITL 2 SPLICING FACTOR 60KDA (PUF60) FROM […]
General Structure Information 2dmk MID2 the solution structure of the fn3 domain of human midline 2 protein -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE FN3 DOMAIN OF HUMANTITL 2 MIDLINE 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3n5n MUTYH crystal structure analysis of the catalytic domain and interdomain connector of human muty homologue 2.3Å AUTH P.J.LUNCSFORD,D.Y.CHANG,G.SHI,J.BERNSTEIN,A.MADABUSHI,AUTH 2 D.N.PATTERSON,A.L.LU,E.A.TOTHTITL A STRUCTURAL HINGE IN EUKARYOTIC MUTY HOMOLOGUES MEDIATESTITL 2 CATALYTIC ACTIVITY AND RAD9-RAD1-HUS1 CHECKPOINT COMPLEXTITL 3 INTERACTIONS.REF J.MOL.BIOL. V. 403 351 2010REFN ISSN 0022-2836PMID 20816984DOI 10.1016/J.JMB.2010.08.045 Variant Set Distributions Ripley’s K […]
General Structure Information 3ffl ANAPC7 crystal structure of the n-terminal domain of anaphase-promoting complex subunit 7 2.5Å AUTH D.HAN,K.KIM,Y.KIM,Y.KANG,Y.KIMTITL CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OFTITL 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2qtl MTRR crystal structure of the fad-containing fnr-like module of human methionine synthase reductase 1.9Å AUTH K.R.WOLTHERS,X.LOU,H.S.TOOGOOD,D.LEYS,N.S.SCRUTTONTITL MECHANISM OF COENZYME BINDING TO HUMAN METHIONINE SYNTHASETITL 2 REDUCTASE REVEALED THROUGH THE CRYSTAL STRUCTURE OF THETITL 3 FNR-LIKE MODULE AND ISOTHERMAL TITRATION CALORIMETRYREF BIOCHEMISTRY V. 46 11833 2007REFN ISSN 0006-2960PMID 17892308DOI 10.1021/BI701209P Variant Set […]
General Structure Information 3aca NUDT5 crystal structure of human nudt5 complexed with 8-oxo-dadp and manganese 2.05Å AUTH T.ARIMORI,H.TAMAOKI,T.NAKAMURA,H.KAMIYA,S.IKEMIZU,Y.TAKAGI,AUTH 2 T.ISHIBASHI,H.HARASHIMA,M.SEKIGUCHI,Y.YAMAGATATITL DIVERSE SUBSTRATE RECOGNITION AND HYDROLYSIS MECHANISMS OFTITL 2 HUMAN NUDT5REF NUCLEIC ACIDS RES. V. 39 8972 2011REFN ISSN 0305-1048PMID 21768126DOI 10.1093/NAR/GKR575 Variant Set Distributions Mapped Variants
General Structure Information 1rz4 EIF3K crystal structure of human eif3k 2.1Å AUTH Z.WEI,P.ZHANG,Z.ZHOU,Z.CHENG,M.WAN,W.GONGTITL CRYSTAL STRUCTURE OF HUMAN EIF3K, THE FIRST STRUCTURE OFTITL 2 EIF3 SUBUNITSREF J.BIOL.CHEM. V. 279 34983 2004REFN ISSN 0021-9258PMID 15180986DOI 10.1074/JBC.M405158200 Variant Set Distributions Mapped Variants