General Structure Information
| PDB ID | 2ch0 |
| HGNC Gene Label(s) | LEMD3 |
| Structure Name | solution structure of the human man1 c-terminal domain (residues 655-775) |
| Resolution | -1.0Å |
| Reference | AUTH S.CAPUTO,J.COUPRIE,I.DUBAND-GOULET,F.LIN,S.BRAUD,AUTH 2 M.GONDRY,H.J.WORMAN,B.GILQUIN,S.ZINN-JUSTINTITL THE CARBOXYL-TERMINAL NUCLEOPLASMIC REGION OF MAN1TITL 2 EXHIBITS A DNA BINDING WINGED HELIX DOMAIN.REF J.BIOL.CHEM. V. 281 18208 2006REFN ISSN 0021-9258PMID 16648637DOI 10.1074/JBC.M601980200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 121 |
| Number Of SNVs | 31 |
| Number Of Permutations | 19292 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.499 |
| p-value | 0.018 |
COSMIC
| Number Of Residues | 121 |
| Number Of SNVs | 6 |
| Number Of Permutations | 3852 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.2 |
| p-value | 0.698 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 31 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.325 |
| p-value | 0.367 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
