3DDT.A | TRIM63

General Structure Information

PDB ID 3ddt
HGNC Gene Label(s) TRIM63
Structure Name crystal structure of the b2 box from murf1 in dimeric state
Resolution 1.9Å
Reference AUTH M.MROSEK,S.MEIER,Z.UCURUM-FOTIADIS,E.VON CASTELMUR,AUTH 2 E.HEDBOM,A.LUSTIG,S.GRZESIEK,D.LABEIT,S.LABEIT,AUTH 3 O.MAYANSTITL STRUCTURAL ANALYSIS OF B-BOX 2 FROM MURF1:TITL 2 IDENTIFICATION OF A NOVEL SELF-ASSOCIATION PATTERNTITL 3 IN A RING-LIKE FOLDREF BIOCHEMISTRY V. 47 10722 2008REFN ISSN 0006-2960PMID 18795805DOI 10.1021/BI800733Z

Variant Set Distributions

ExAC Variants

Number Of Residues 45
Number Of SNVs 16
Number Of Permutations 737
Optimal Distance Threshold 5.0
K Statistic 0.025
p-value 0.773
COSMIC

Number Of Residues 45
Number Of SNVs 3
Number Of Permutations 1
Optimal Distance Threshold 8.0
K Statistic 0.333
p-value 1.0

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 16
Number Of COSMIC SNVs 3
Optimal Distance Threshold 7.0
K Statistic -0.15
p-value 0.89

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants