3V30.A | RFXANK

General Structure Information 3v30 RFXANK crystal structure of the peptide bound complex of the ankyrin repeat domains of human rfxank 1.57Å AUTH C.XU,J.JIN,C.BIAN,R.LAM,R.TIAN,R.WEIST,L.YOU,J.NIE,AUTH 2 A.BOCHKAREV,W.TEMPEL,C.S.TAN,G.A.WASNEY,M.VEDADI,G.D.GISH,AUTH 3 C.H.ARROWSMITH,T.PAWSON,X.J.YANG,J.MINTITL SEQUENCE-SPECIFIC RECOGNITION OF A PXLPXI/L MOTIF BY ANTITL 2 ANKYRIN REPEAT TUMBLER LOCK.REF SCI.SIGNAL. V. 5 RA39 2012REFN ESSN 1937-9145PMID 22649097DOI 10.1126/SCISIGNAL.2002979 Variant Set Distributions Ripley’s K Analysis […]

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2ZFU.A | RRP8

General Structure Information 2zfu RRP8 structure of the methyltransferase-like domain of nucleomethylin 2.0Å AUTH A.MURAYAMA,K.OHMORI,A.FUJIMURA,H.MINAMI,K.YASUZAWA-TANAKA,AUTH 2 T.KURODA,S.OIE,H.DAITOKU,M.OKUWAKI,K.NAGATA,A.FUKAMIZU,AUTH 3 K.KIMURA,T.SHIMIZU,J.YANAGISAWATITL EPIGENETIC CONTROL OF RDNA LOCI IN RESPONSE TO INTRACELLULARTITL 2 ENERGY STATUSREF CELL(CAMBRIDGE,MASS.) V. 133 627 2008REFN ISSN 0092-8674PMID 18485871DOI 10.1016/J.CELL.2008.03.030 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants

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1HTJ.F | ARHGEF11

General Structure Information 1htj ARHGEF11 structure of the rgs-like domain from pdz-rhogef 2.2Å AUTH K.L.LONGENECKER,M.E.LEWIS,H.CHIKUMI,J.S.GUTKIND,AUTH 2 Z.S.DEREWENDATITL STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF:TITL 2 LINKING HETEROTRIMERIC G PROTEIN-COUPLED SIGNALINGTITL 3 TO RHO GTPASES.REF STRUCTURE V. 9 559 2001REFN ISSN 0969-2126PMID 11470431DOI 10.1016/S0969-2126(01)00620-7 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]

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1DK8.A | AXIN1

General Structure Information 1dk8 AXIN1 crystal structure of the rgs-homologous domain of axin 1.57Å AUTH K.E.SPINK,P.POLAKIS,W.I.WEISTITL STRUCTURAL BASIS OF THE AXIN-ADENOMATOUS POLYPOSIS COLITITL 2 INTERACTION.REF EMBO J. V. 19 2270 2000REFN ISSN 0261-4189PMID 10811618DOI 10.1093/EMBOJ/19.10.2270 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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3AL5.A | TYW5

General Structure Information 3al5 TYW5 crystal structure of human tyw5 2.5Å AUTH M.KATO,Y.ARAISO,A.NOMA,A.NAGAO,T.SUZUKI,R.ISHITANI,O.NUREKITITL CRYSTAL STRUCTURE OF A NOVEL JMJC-DOMAIN-CONTAINING PROTEIN,TITL 2 TYW5, INVOLVED IN TRNA MODIFICATION.REF NUCLEIC ACIDS RES. V. 39 1576 2011REFN ISSN 0305-1048PMID 20972222DOI 10.1093/NAR/GKQ919 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants

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2E70.A | SUPT5H

General Structure Information 2e70 SUPT5H solution structure of the fifth kow motif of human transcription elongation factor spt5 -1.0Å AUTH W.TANABE,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH KOW MOTIF OF HUMANTITL 2 TRANSCRIPTION ELONGATION FACTOR SPT5REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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4NRE.A | ALOX15B

General Structure Information 4nre ALOX15B the structure of human 15-lipoxygenase-2 with a substrate mimic 2.63Å AUTH M.J.KOBE,D.B.NEAU,C.E.MITCHELL,S.G.BARTLETT,M.E.NEWCOMERTITL THE STRUCTURE OF HUMAN 15-LIPOXYGENASE-2 WITH A SUBSTRATETITL 2 MIMIC.REF J.BIOL.CHEM. V. 289 8562 2014REFN ISSN 0021-9258PMID 24497644DOI 10.1074/JBC.M113.543777 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants

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3GEB.A | EYA2

General Structure Information 3geb EYA2 crystal structure of edeya2 2.4Å AUTH S.J.KIM,D.G.JEONG,S.K.JUNG,E.R.SEONGTITL STRUCTURE OF EDEYA2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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3LLK.A | QSOX1

General Structure Information 3llk QSOX1 sulfhydryl oxidase fragment of human qsox1 2.0Å AUTH A.ALON,E.J.HECKLER,C.THORPE,D.FASSTITL QSOX CONTAINS A PSEUDO-DIMER OF FUNCTIONAL AND DEGENERATETITL 2 SULFHYDRYL OXIDASE DOMAINS.REF FEBS LETT. V. 584 1521 2010REFN ISSN 0014-5793PMID 20211621DOI 10.1016/J.FEBSLET.2010.03.001 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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2DYL.A | MAP2K7

General Structure Information 2dyl MAP2K7 crystal structure of human mitogen-activated protein kinase kinase 7 activated mutant (s287d, t291d) 2.45Å AUTH M.KUKIMOTO-NIINO,T.TAKAGI,T.KAMINISHI,AUTH 2 T.UCHIKUBO-KAMO,T.TERADA,O.MATSUZAKI,M.SHIROUZU,AUTH 3 S.YOKOYAMATITL CRYSTAL STRUCTURE OF HUMAN MITOGEN-ACTIVATEDTITL 2 PROTEIN KINASE KINASE 7 ACTIVATED MUTANT (S287D,TITL 3 T291D)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]

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