General Structure Information
| PDB ID | 1dk8 |
| HGNC Gene Label(s) | AXIN1 |
| Structure Name | crystal structure of the rgs-homologous domain of axin |
| Resolution | 1.57Å |
| Reference | AUTH K.E.SPINK,P.POLAKIS,W.I.WEISTITL STRUCTURAL BASIS OF THE AXIN-ADENOMATOUS POLYPOSIS COLITITL 2 INTERACTION.REF EMBO J. V. 19 2270 2000REFN ISSN 0261-4189PMID 10811618DOI 10.1093/EMBOJ/19.10.2270 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 147 |
| Number Of SNVs | 32 |
| Number Of Permutations | 24866 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.141 |
| p-value | 0.741 |
COSMIC
| Number Of Residues | 147 |
| Number Of SNVs | 8 |
| Number Of Permutations | 2656 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.071 |
| p-value | 0.948 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 32 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.046 |
| p-value | 0.627 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
