General Structure Information
| PDB ID | 3v30 |
| HGNC Gene Label(s) | RFXANK |
| Structure Name | crystal structure of the peptide bound complex of the ankyrin repeat domains of human rfxank |
| Resolution | 1.57Å |
| Reference | AUTH C.XU,J.JIN,C.BIAN,R.LAM,R.TIAN,R.WEIST,L.YOU,J.NIE,AUTH 2 A.BOCHKAREV,W.TEMPEL,C.S.TAN,G.A.WASNEY,M.VEDADI,G.D.GISH,AUTH 3 C.H.ARROWSMITH,T.PAWSON,X.J.YANG,J.MINTITL SEQUENCE-SPECIFIC RECOGNITION OF A PXLPXI/L MOTIF BY ANTITL 2 ANKYRIN REPEAT TUMBLER LOCK.REF SCI.SIGNAL. V. 5 RA39 2012REFN ESSN 1937-9145PMID 22649097DOI 10.1126/SCISIGNAL.2002979 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 161 |
| Number Of SNVs | 53 |
| Number Of Permutations | 24781 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.066 |
| p-value | 0.118 |
COSMIC
| Number Of Residues | 161 |
| Number Of SNVs | 4 |
| Number Of Permutations | 943 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.167 |
| p-value | 0.708 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | -0.452 |
| p-value | 0.224 |