Assessment of Structural Intolerance and Durability
General Structure Information 1ryu ARID1A solution structure of the swi1 arid -1.0Å AUTH S.KIM,Z.ZHANG,S.UPCHURCH,N.ISERN,Y.CHENTITL STRUCTURE AND DNA-BINDING SITES OF THE SWI1TITL 2 AT-RICH INTERACTION DOMAIN (ARID) SUGGESTTITL 3 DETERMINANTS FOR SEQUENCE-SPECIFIC DNA RECOGNITION.REF J.BIOL.CHEM. V. 279 16670 2004REFN ISSN 0021-9258PMID 14722072DOI 10.1074/JBC.M312115200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2p0a SYN3 the crystal structure of human synapsin iii (syn3) in complex with amppnp 1.9Å AUTH A.P.TURNBULL,C.PHILLIPS,A.C.W.PIKE,J.M.ELKINS,C.GILEADI,AUTH 2 E.SALAH,F.H.NIESEN,N.BURGESS,O.GILEADI,F.GORREC,C.UMEANO,AUTH 3 F.VON DELFT,J.WEIGELT,A.EDWARDS,C.H.ARROWSMITH,M.SUNDSTROM,AUTH 4 D.DOYLETITL THE CRYSTAL STRUCTURE OF HUMAN SYNAPSIN III (SYN3) INTITL 2 COMPLEX WITH AMPPNPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2fic BIN1 the crystal structure of the bar domain from human bin1/amphiphysin ii and its implications for molecular recognition 1.99Å AUTH E.CASAL,L.FEDERICI,W.ZHANG,J.FERNANDEZ-RECIO,E.M.PRIEGO,AUTH 2 R.N.MIGUEL,J.B.DUHADAWAY,G.C.PRENDERGAST,B.F.LUISI,E.D.LAUETITL THE CRYSTAL STRUCTURE OF THE BAR DOMAIN FROM HUMANTITL 2 BIN1/AMPHIPHYSIN II AND ITS IMPLICATIONS FOR MOLECULARTITL 3 RECOGNITIONREF BIOCHEMISTRY V. 45 12917 2006REFN ISSN 0006-2960PMID 17059209DOI 10.1021/BI060717K […]
General Structure Information 1wwy TXNL1 solution structure of the duf1000 domain of a thioredoxin-like protein 1 -1.0Å AUTH A.K.GORONCY,S.KOSHIBA,N.TOCHIO,T.TOMIZAWA,M.INOUE,A.TANAKA,AUTH 2 S.SUGANO,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL DUF1000 DOMAIN OF THETITL 2 HUMAN THIOREDOXIN-LIKE 1 PROTEIN.REF PROTEINS V. 78 2176 2010REFN ISSN 0887-3585PMID 20455272DOI 10.1002/PROT.22719 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2d8k SYT7 solution structure of the first c2 domain of synaptotagmin vii -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OFTITL 2 SYNAPTOTAGMIN VIIREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2per CLIC2 crystal structure of human chloride intracellular channel protein 2 2.0Å AUTH W.MI,Y.H.LIANG,L.LI,X.D.SUTITL THE CRYSTAL STRUCTURE OF HUMAN CHLORIDETITL 2 INTRACELLULAR CHANNEL PROTEIN 2: A DISULFIDE BONDTITL 3 WITH FUNCTIONAL IMPLICATIONS.REF PROTEINS V. 71 509 2008REFN ISSN 0887-3585PMID 18186468DOI 10.1002/PROT.21922 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 3vkm LGALS8 protease-resistant mutant form of human galectin-8 in complex with sialyllactose and lactose 2.98Å AUTH H.YOSHIDA,S.YAMASHITA,M.TERAOKA,A.ITOH,S.NAKAKITA,N.NISHI,AUTH 2 S.KAMITORITITL X-RAY STRUCTURE OF A PROTEASE-RESISTANT MUTANT FORM OF HUMANTITL 2 GALECTIN-8 WITH TWO CARBOHYDRATE RECOGNITION DOMAINSREF FEBS J. V. 279 3937 2012REFN ISSN 1742-464XPMID 22913484DOI 10.1111/J.1742-4658.2012.08753.X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3ibj PDE2A x-ray structure of pde2a 3.02Å AUTH J.PANDIT,M.D.FORMAN,K.F.FENNELL,K.S.DILLMAN,F.S.MENNITITITL MECHANISM FOR THE ALLOSTERIC REGULATION OF PHOSPHODIESTERASETITL 2 2A DEDUCED FROM THE X-RAY STRUCTURE OF A NEAR FULL-LENGTHTITL 3 CONSTRUCT.REF PROC.NATL.ACAD.SCI.USA V. 106 18225 2009REFN ISSN 0027-8424PMID 19828435DOI 10.1073/PNAS.0907635106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3ulv TLR3 structure of quaternary complex of human tlr3ecd with three fabs (form2) 3.52Å AUTH J.LUO,G.OBMOLOVA,T.J.MALIA,S.J.WU,K.E.DUFFY,J.D.MARION,AUTH 2 J.K.BELL,P.GE,Z.H.ZHOU,A.TEPLYAKOV,Y.ZHAO,R.J.LAMB,AUTH 3 J.L.JORDAN,L.R.SAN MATEO,R.W.SWEET,G.L.GILLILANDTITL LATERAL CLUSTERING OF TLR3:DSRNA SIGNALING UNITS REVEALED BYTITL 2 TLR3ECD:3FABS QUATERNARY STRUCTURE.REF J.MOL.BIOL. V. 421 112 2012REFN ISSN 0022-2836PMID 22579623DOI 10.1016/J.JMB.2012.05.006 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3ee6 TPP1 crystal structure analysis of tripeptidyl peptidase -i 2.35Å AUTH A.PAL,R.KRAETZNER,T.GRUENE,M.GRAPP,K.SCHREIBER,M.GRONBORG,AUTH 2 H.URLAUB,S.BECKER,A.R.ASIF,J.GARTNER,G.M.SHELDRICK,AUTH 3 R.STEINFELDTITL STRUCTURE OF TRIPEPTIDYL-PEPTIDASE I PROVIDES INSIGHT INTOTITL 2 THE MOLECULAR BASIS OF LATE INFANTILE NEURONAL CEROIDTITL 3 LIPOFUSCINOSISREF J.BIOL.CHEM. V. 284 3976 2009REFN ISSN 0021-9258PMID 19038966DOI 10.1074/JBC.M806947200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]