General Structure Information
| PDB ID | 2p0a |
| HGNC Gene Label(s) | SYN3 |
| Structure Name | the crystal structure of human synapsin iii (syn3) in complex with amppnp |
| Resolution | 1.9Å |
| Reference | AUTH A.P.TURNBULL,C.PHILLIPS,A.C.W.PIKE,J.M.ELKINS,C.GILEADI,AUTH 2 E.SALAH,F.H.NIESEN,N.BURGESS,O.GILEADI,F.GORREC,C.UMEANO,AUTH 3 F.VON DELFT,J.WEIGELT,A.EDWARDS,C.H.ARROWSMITH,M.SUNDSTROM,AUTH 4 D.DOYLETITL THE CRYSTAL STRUCTURE OF HUMAN SYNAPSIN III (SYN3) INTITL 2 COMPLEX WITH AMPPNPREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 298 |
| Number Of SNVs | 73 |
| Number Of Permutations | 35082 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.019 |
| p-value | 0.731 |
COSMIC
| Number Of Residues | 298 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1145 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.4 |
| p-value | 0.375 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 73 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.212 |
| p-value | 0.449 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
