General Structure Information
| PDB ID | 2per |
| HGNC Gene Label(s) | CLIC2 |
| Structure Name | crystal structure of human chloride intracellular channel protein 2 |
| Resolution | 2.0Å |
| Reference | AUTH W.MI,Y.H.LIANG,L.LI,X.D.SUTITL THE CRYSTAL STRUCTURE OF HUMAN CHLORIDETITL 2 INTRACELLULAR CHANNEL PROTEIN 2: A DISULFIDE BONDTITL 3 WITH FUNCTIONAL IMPLICATIONS.REF PROTEINS V. 71 509 2008REFN ISSN 0887-3585PMID 18186468DOI 10.1002/PROT.21922 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 222 |
| Number Of SNVs | 28 |
| Number Of Permutations | 3978 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.209 |
| p-value | 0.087 |
COSMIC
| Number Of Residues | 222 |
| Number Of SNVs | 5 |
| Number Of Permutations | 617 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.6 |
| p-value | 0.011 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 28 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.767 |
| p-value | 0.008 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
