General Structure Information
| PDB ID | 1wwy |
| HGNC Gene Label(s) | TXNL1 |
| Structure Name | solution structure of the duf1000 domain of a thioredoxin-like protein 1 |
| Resolution | -1.0Å |
| Reference | AUTH A.K.GORONCY,S.KOSHIBA,N.TOCHIO,T.TOMIZAWA,M.INOUE,A.TANAKA,AUTH 2 S.SUGANO,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL DUF1000 DOMAIN OF THETITL 2 HUMAN THIOREDOXIN-LIKE 1 PROTEIN.REF PROTEINS V. 78 2176 2010REFN ISSN 0887-3585PMID 20455272DOI 10.1002/PROT.22719 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 158 |
| Number Of SNVs | 30 |
| Number Of Permutations | 3163 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.166 |
| p-value | 0.27 |
COSMIC
| Number Of Residues | 158 |
| Number Of SNVs | 4 |
| Number Of Permutations | 16 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.167 |
| p-value | 0.981 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 30 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.355 |
| p-value | 0.298 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
