Assessment of Structural Intolerance and Durability
General Structure Information 2enp SYT17 solution structure of the first c2 domain from human b/k protein -1.0Å AUTH H.ENDO,T.NAGASHIMA,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN FROMTITL 2 HUMAN B/K PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2rlo AGAP2 split ph domain of pi3-kinase enhancer -1.0Å AUTH J.YAN,W.WEN,L.N.CHAN,M.ZHANGTITL SPLIT PLECKSTRIN HOMOLOGY DOMAIN-MEDIATEDTITL 2 CYTOPLASMIC-NUCLEAR LOCALIZATION OF PI3-KINASETITL 3 ENHANCER GTPASEREF J.MOL.BIOL. V. 378 425 2008REFN ISSN 0022-2836PMID 18371979DOI 10.1016/J.JMB.2008.02.052 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4hmy AP1S3 structural basis for recruitment and activation of the ap-1 clathrin adaptor complex by arf1 7.0Å AUTH X.REN,G.G.FARIAS,B.J.CANAGARAJAH,J.S.BONIFACINO,J.H.HURLEYTITL STRUCTURAL BASIS FOR RECRUITMENT AND ACTIVATION OF THE AP-1TITL 2 CLATHRIN ADAPTOR COMPLEX BY ARF1.REF CELL(CAMBRIDGE,MASS.) V. 152 755 2013REFN ISSN 0092-8674PMID 23415225DOI 10.1016/J.CELL.2012.12.042 Variant Set Distributions Mapped Variants
General Structure Information 1wou TXNDC17 crystal structure of human trp14 1.8Å AUTH J.R.WOO,S.J.KIM,W.JEONG,Y.H.CHO,S.C.LEE,Y.J.CHUNG,AUTH 2 S.G.RHEE,S.E.RYUTITL STRUCTURAL BASIS OF CELLULAR REDOX REGULATION BYTITL 2 HUMAN TRP14REF J.BIOL.CHEM. V. 279 48120 2004REFN ISSN 0021-9258PMID 15355959DOI 10.1074/JBC.M407079200 Variant Set Distributions Mapped Variants
General Structure Information 3edt KLC2 crystal structure of the mutated s328n hklc2 tpr domain 2.7Å AUTH H.ZHU,Y.SHEN,F.MACKENZIE,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF MUTATED S328N TPR DOMAIN OF HUMANTITL 2 KINESIN LIGHT CHAIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2v66 NDEL1 crystal structure of the coiled-coil domain of ndel1 (a.a. 58 to 169)c 2.1Å AUTH U.DEREWENDA,C.TARRICONE,W.C.CHOI,D.R.COOPER,S.LUKASIK,AUTH 2 F.PERRINA,A.TRIPATHY,M.H.KIM,D.S.CAFISO,A.MUSACCHIO,AUTH 3 Z.S.DEREWENDATITL THE STRUCTURE OF THE COILED-COIL DOMAIN OF NDEL1 AND THETITL 2 BASIS OF ITS INTERACTION WITH LIS1, THE CAUSAL PROTEIN OFTITL 3 MILLER-DIEKER LISSENCEPHALY.REF STRUCTURE V. 15 1467 2007REFN ISSN 0969-2126PMID […]
General Structure Information 2h58 KIFC3 crystal structure of the kifc3 motor domain in complex with adp 1.85Å AUTH J.WANG,Y.SHEN,W.TEMPEL,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE KIFC3 MOTOR DOMAIN INTITL 2 COMPLEX WITH ADPREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3iv1 TSG101 coiled-coil domain of tumor susceptibility gene 101 2.5Å AUTH D.NECULAI,G.V.AVVAKUMOV,A.K.WERNIMONT,S.XUE,AUTH 2 J.R.WALKER,Y.LI,J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL COILED-COIL DOMAIN OF HUMAN TSG101REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yqm RUFY1 solution structure of the fyve domain in zinc finger fyve domain-containing protein 12 -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FYVE DOMAIN IN ZINCTITL 2 FINGER FYVE DOMAIN-CONTAINING PROTEIN 12REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d9x OSBPL11 solution structure of the ph domain of oxysterol binding protein-related protein 11 from human -1.0Å AUTH H.LI,M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF OXYSTEROLTITL 2 BINDING PROTEIN-RELATED PROTEIN 11 FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants