Assessment of Structural Intolerance and Durability
General Structure Information 2ept ZNF32 solution structure of the first c2h2 type zinc finger domain of zinc finger protein 32 -1.0Å AUTH W.TANABE,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 32REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3dzu RXRA intact ppar gamma – rxr alpha nuclear receptor complex on dna bound with bvt.13, 9-cis retinoic acid and ncoa2 peptide 3.2Å AUTH V.CHANDRA,P.HUANG,Y.HAMURO,S.RAGHURAM,Y.WANG,T.P.BURRIS,AUTH 2 F.RASTINEJADTITL STRUCTURE OF THE INTACT PPAR-GAMMA-RXR- NUCLEAR RECEPTORTITL 2 COMPLEX ON DNA.REF NATURE V. 456 350 2008REFN ISSN 0028-0836PMID 19043829DOI 10.1038/NATURE07413 Variant Set Distributions Ripley’s K […]
General Structure Information 4mhv ETS2 crystal structure of the pnt domain of human ets2 2.45Å AUTH J.A.NEWMAN,C.D.O.COOPER,T.KROJER,L.SHRESTHA,N.BURGESS-BROWN,AUTH 2 C.H.ARROWSMITH,C.BOUNTRA,A.EDWARDS,O.GILEADITITL CRYSTAL STRUCTURE OF THE PNT DOMAIN OF HUMAN ETS2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lhr ZNF24 crystal structure of the scan domain from human znf24 1.9Å AUTH B.F.VOLKMAN,F.C.PETERSON,C.A.BINGMAN,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF THE SCAN DOMAIN FROM HUMAN ZNF24REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ebl NR2F1 solution structure of the zinc finger, c4-type domain of human coup transcription factor 1 -1.0Å AUTH M.YONEYAMA,S.KOSHIBA,S.WATABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZINC FINGER, C4-TYPETITL 2 DOMAIN OF HUMAN COUP TRANSCRIPTION FACTOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2aze RB1 structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer 2.55Å AUTH S.M.RUBIN,A.L.GALL,N.ZHENG,N.P.PAVLETICHTITL STRUCTURE OF THE RB C-TERMINAL DOMAIN BOUND TOTITL 2 E2F1-DP1: A MECHANISM FOR PHOSPHORYLATION-INDUCEDTITL 3 E2F RELEASE.REF CELL(CAMBRIDGE,MASS.) V. 123 1093 2005REFN ISSN 0092-8674PMID 16360038DOI 10.1016/J.CELL.2005.09.044 Variant Set Distributions Mapped Variants
General Structure Information 2aa6 NR3C2 mineralocorticoid receptor s810l mutant with bound progesterone 1.95Å AUTH R.K.BLEDSOE,K.P.MADAUSS,J.A.HOLT,C.J.APOLITO,AUTH 2 M.H.LAMBERT,K.H.PEARCE,T.B.STANLEY,E.L.STEWART,AUTH 3 R.P.TRUMP,T.M.WILLSON,S.P.WILLIAMSTITL A LIGAND-MEDIATED HYDROGEN BOND NETWORK REQUIREDTITL 2 FOR THE ACTIVATION OF THE MINERALOCORTICOIDTITL 3 RECEPTORREF J.BIOL.CHEM. V. 280 31283 2005REFN ISSN 0021-9258PMID 15967794DOI 10.1074/JBC.M504098200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4h5n HSPA8 hsc70 nbd with po4, na, cl 1.86Å AUTH Z.ZHANG,J.CELLITTI,P.TERIETE,M.PELLECCHIA,B.STECTITL NEW CRYSTAL STRUCTURES OF HSC-70 ATP BINDING DOMAIN CONFIRMTITL 2 THE ROLE OF INDIVIDUAL BINDING POCKETS AND SUGGEST A NEWTITL 3 METHOD OF INHIBITION.REF BIOCHIMIE V. 108 186 2015REFN ISSN 0300-9084PMID 25433210DOI 10.1016/J.BIOCHI.2014.11.012 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3b97 ENO1 crystal structure of human enolase 1 2.2Å AUTH H.J.KANG,S.K.JUNG,S.J.KIM,S.J.CHUNGTITL STRUCTURE OF HUMAN ALPHA-ENOLASE (HENO1), ATITL 2 MULTIFUNCTIONAL GLYCOLYTIC ENZYME.REF ACTA CRYSTALLOGR.,SECT.D V. 64 651 2008REFN ISSN 0907-4449PMID 18560153DOI 10.1107/S0907444908008561 Variant Set Distributions Mapped Variants
General Structure Information 1sxe ERG the solution structure of the pointed (pnt) domain from the transcrition factor erg -1.0Å AUTH C.D.MACKERETH,M.SCHAERPF,L.N.GENTILE,S.E.MACINTOSH,AUTH 2 C.M.SLUPSKY,L.P.MCINTOSHTITL DIVERSITY IN STRUCTURE AND FUNCTION OF THE ETSTITL 2 FAMILY PNT DOMAINS.REF J.MOL.BIOL. V. 342 1249 2004REFN ISSN 0022-2836PMID 15351649DOI 10.1016/J.JMB.2004.07.094 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]