General Structure Information
| PDB ID | 1sxe |
| HGNC Gene Label(s) | ERG |
| Structure Name | the solution structure of the pointed (pnt) domain from the transcrition factor erg |
| Resolution | -1.0Å |
| Reference | AUTH C.D.MACKERETH,M.SCHAERPF,L.N.GENTILE,S.E.MACINTOSH,AUTH 2 C.M.SLUPSKY,L.P.MCINTOSHTITL DIVERSITY IN STRUCTURE AND FUNCTION OF THE ETSTITL 2 FAMILY PNT DOMAINS.REF J.MOL.BIOL. V. 342 1249 2004REFN ISSN 0022-2836PMID 15351649DOI 10.1016/J.JMB.2004.07.094 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 94 |
| Number Of SNVs | 15 |
| Number Of Permutations | 1102 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.076 |
| p-value | 0.799 |
COSMIC
| Number Of Residues | 94 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 15 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.329 |
| p-value | 0.57 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
