Assessment of Structural Intolerance and Durability
General Structure Information 1n11 ANK1 d34 region of human ankyrin-r and linker 2.7Å AUTH P.MICHAELY,D.R.TOMCHICK,M.MACHIUS,R.G.W.ANDERSONTITL CRYSTAL STRUCTURE OF A 12 ANK REPEAT STACK FROMTITL 2 HUMAN ANKYRINRREF EMBO J. V. 21 6387 2002REFN ISSN 0261-4189PMID 12456646DOI 10.1093/EMBOJ/CDF651 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1lm5 DSP structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure 1.8Å AUTH H.J.CHOI,S.PARK-SNYDER,L.T.PASCOE,K.J.GREEN,AUTH 2 W.I.WEISTITL STRUCTURES OF TWO INTERMEDIATE FILAMENT-BINDINGTITL 2 FRAGMENTS OF DESMOPLAKIN REVEAL A UNIQUE REPEATTITL 3 MOTIF STRUCTURE.REF NAT.STRUCT.BIOL. V. 9 612 2002REFN ISSN 1072-8368PMID 12101406 Variant Set Distributions Mapped Variants
General Structure Information 2acm MUC1 solution structure of the sea domain of human mucin 1 (muc1) -1.0Å AUTH B.MACAO,D.G.A.JOHANSSON,G.C.HANSSON,T.HARDTITL AUTOPROTEOLYSIS COUPLED TO PROTEIN FOLDING IN THETITL 2 SEA DOMAIN OF THE MEMBRANE-BOUND MUC1 MUCINREF NAT.STRUCT.MOL.BIOL. V. 13 71 2006REFN ISSN 1545-9993PMID 16369486DOI 10.1038/NSMB1035 Variant Set Distributions Mapped Variants
General Structure Information 3f7p ITGB4 crystal structure of a complex between integrin beta4 and plectin 2.75Å AUTH J.M.DE PEREDA,M.P.LILLO,A.SONNENBERGTITL STRUCTURAL BASIS OF THE INTERACTION BETWEENTITL 2 INTEGRIN ALPHA6BETA4 AND PLECTIN AT THETITL 3 HEMIDESMOSOMESREF EMBO J. V. 28 1180 2009REFN ISSN 0261-4189PMID 19242489DOI 10.1038/EMBOJ.2009.48 Variant Set Distributions Mapped Variants
General Structure Information 2eyi ACTN1 crystal structure of the actin-binding domain of human alpha-actinin 1 at 1.7 angstrom resolution 1.7Å AUTH E.BORREGO-DIAZ,F.KERFF,S.H.LEE,F.FERRON,Y.LI,AUTH 2 R.DOMINGUEZTITL CRYSTAL STRUCTURE OF THE ACTIN-BINDING DOMAIN OFTITL 2 ALPHA-ACTININ 1: EVALUATING TWO COMPETINGTITL 3 ACTIN-BINDING MODELS.REF J.STRUCT.BIOL. V. 155 230 2006REFN ISSN 1047-8477PMID 16698282DOI 10.1016/J.JSB.2006.01.013 Variant Set Distributions Pathogenic Proximity Analysis […]
General Structure Information 1s35 SPTB crystal structure of repeats 8 and 9 of human erythroid spectrin 2.4Å AUTH H.KUSUNOKI,R.I.MACDONALD,A.MONDRAGONTITL STRUCTURAL INSIGHTS INTO THE STABILITY ANDTITL 2 FLEXIBILITY OF UNUSUAL ERYTHROID SPECTRIN REPEATSREF STRUCTURE V. 12 645 2004REFN ISSN 0969-2126PMID 15062087DOI 10.1016/J.STR.2004.02.022 Variant Set Distributions Mapped Variants
General Structure Information 2jdf CRYGB human gamma-b crystallin 1.7Å AUTH H.EBERSBACH,E.FIEDLER,T.SCHEUERMANN,M.FIEDLER,AUTH 2 M.T.STUBBS,C.REIMANN,G.PROETZEL,R.RUDOLPH,U.FIEDLERTITL AFFILIN-NOVEL BINDING MOLECULES BASED ON HUMANTITL 2 GAMMA-B-CRYSTALLIN, AN ALL BETA-SHEET PROTEIN.REF J.MOL.BIOL. V. 372 172 2007REFN ISSN 0022-2836PMID 17628592DOI 10.1016/J.JMB.2007.06.045 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3kbt SPTB crystal structure of the ankyrin binding domain of human erythroid beta spectrin (repeats 13-15) in complex with the spectrin binding domain of human erythroid ankyrin (zu5-ank) 2.75Å AUTH J.J.IPSARO,A.MONDRAGONTITL STRUCTURAL BASIS FOR SPECTRIN RECOGNITION BY ANKYRIN.REF BLOOD V. 115 4093 2010REFN ISSN 0006-4971PMID 20101027DOI 10.1182/BLOOD-2009-11-255604 Variant Set Distributions Ripley’s K […]
General Structure Information 3uf1 VIM crystal structure of vimentin (fragment 144-251) from homo sapiens, northeast structural genomics consortium target hr4796b 2.81Å AUTH A.AZIZ,J.F.HESS,M.S.BUDAMAGUNTA,J.C.VOSS,A.P.KUZIN,AUTH 2 Y.J.HUANG,R.XIAO,G.T.MONTELIONE,P.G.FITZGERALD,J.F.HUNTTITL THE STRUCTURE OF VIMENTIN LINKER 1 AND ROD 1B DOMAINSTITL 2 CHARACTERIZED BY SITE-DIRECTED SPIN-LABELING ELECTRONTITL 3 PARAMAGNETIC RESONANCE (SDSL-EPR) AND X-RAY CRYSTALLOGRAPHY.REF J.BIOL.CHEM. V. 287 28349 2012REFN ISSN 0021-9258PMID […]
General Structure Information 3klt VIM crystal structure of a vimentin fragment 2.7Å AUTH S.NICOLET,H.HERRMANN,U.AEBI,S.V.STRELKOVTITL ATOMIC STRUCTURE OF VIMENTIN COIL 2.REF J.STRUCT.BIOL. V. 170 369 2010REFN ISSN 1047-8477PMID 20176112DOI 10.1016/J.JSB.2010.02.012 Variant Set Distributions Mapped Variants