3UF1.A | VIM

General Structure Information

PDB ID 3uf1
HGNC Gene Label(s) VIM
Structure Name crystal structure of vimentin (fragment 144-251) from homo sapiens, northeast structural genomics consortium target hr4796b
Resolution 2.81Å
Reference AUTH A.AZIZ,J.F.HESS,M.S.BUDAMAGUNTA,J.C.VOSS,A.P.KUZIN,AUTH 2 Y.J.HUANG,R.XIAO,G.T.MONTELIONE,P.G.FITZGERALD,J.F.HUNTTITL THE STRUCTURE OF VIMENTIN LINKER 1 AND ROD 1B DOMAINSTITL 2 CHARACTERIZED BY SITE-DIRECTED SPIN-LABELING ELECTRONTITL 3 PARAMAGNETIC RESONANCE (SDSL-EPR) AND X-RAY CRYSTALLOGRAPHY.REF J.BIOL.CHEM. V. 287 28349 2012REFN ISSN 0021-9258PMID 22740688DOI 10.1074/JBC.M111.334011

Variant Set Distributions

ExAC Variants

Number Of Residues 101
Number Of SNVs 28
Number Of Permutations 17719
Optimal Distance Threshold 9.0
K Statistic 0.09
p-value 0.873
COSMIC

Number Of Residues 101
Number Of SNVs 3
Number Of Permutations 421
Optimal Distance Threshold 11.0
K Statistic 0.333
p-value 0.889

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants