General Structure Information
| PDB ID | 2jdf |
| HGNC Gene Label(s) | CRYGB |
| Structure Name | human gamma-b crystallin |
| Resolution | 1.7Å |
| Reference | AUTH H.EBERSBACH,E.FIEDLER,T.SCHEUERMANN,M.FIEDLER,AUTH 2 M.T.STUBBS,C.REIMANN,G.PROETZEL,R.RUDOLPH,U.FIEDLERTITL AFFILIN-NOVEL BINDING MOLECULES BASED ON HUMANTITL 2 GAMMA-B-CRYSTALLIN, AN ALL BETA-SHEET PROTEIN.REF J.MOL.BIOL. V. 372 172 2007REFN ISSN 0022-2836PMID 17628592DOI 10.1016/J.JMB.2007.06.045 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 174 |
| Number Of SNVs | 60 |
| Number Of Permutations | 6053 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.108 |
| p-value | 0.746 |
COSMIC
| Number Of Residues | 174 |
| Number Of SNVs | 6 |
| Number Of Permutations | 716 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.2 |
| p-value | 0.274 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.241 |
| p-value | 0.091 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
